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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
AMX0035 Amyotrophic Lateral Sclerosis (Phase 2), Alzheimer's Disease (Phase 2) Amylyx Pharmaceuticals Inc Other Combination, Small Molecule
ATH-1017 NDX-1017 Alzheimer's Disease (Phase 2) Athira Pharma Other Small Molecule
BPN14770 Alzheimer's Disease (Phase 2) Shionogi Pharma, Tetra Therapeutics Cholinergic System, Other Small Molecule
Bifidobacterium breve A1 MCC1274,
B. breve
Mild Cognitive Impairment (Phase 2) Morinaga Milk Industry Co., Ltd Other Supplement, Dietary
Bosutinib BOSULIF®,
PF-5208763,
SKI-606
Alzheimer's Disease (Phase 2), Dementia with Lewy Bodies (Phase 2) Pfizer Other Small Molecule Chronic myeloid leukemia
Bryostatin 1 Alzheimer's Disease (Phase 2) Neurotrope Other Other
Candesartan Atacand,
Candesartan cilexetil
Mild Cognitive Impairment (Phase 2), Alzheimer's Disease (Phase 2) AstraZeneca, Takeda Pharmaceutical Company Other Small Molecule Hypertension, congestive heart failure
Cerebrolysin Alzheimer's Disease (Phase 2) Ebewe Pharmaceutical Other Other
Circadin Alzheimer's Disease (Phase 2) Neurim Pharmaceuticals Ltd. Other Small Molecule Insomnia
Curcumin diferuloylmethane,
Longvida™
Alzheimer's Disease (Phase 2) Verdure Sciences Other, Unknown Supplement, Dietary None
DAYVIGO Lemborexant,
E2006
Alzheimer's Disease (Phase 2) Eisai Co., Ltd. Other Small Molecule Insomnia
Dexpramipexole R-pramipexole,
RPPX,
KNS-760704 ,
BIIB 050
Alzheimer's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Discontinued) Biogen, Knopp Biosciences LLC, Virginia Commonwealth University Other Neurotransmitters, Other Small Molecule
EHT 0202 Etazolate Alzheimer's Disease (Phase 2) ExonHit Therapeutics Other Small Molecule None
G-CSF Filgrastim Alzheimer's Disease (Phase 2) Other Small Molecule Neutropenia in US
GM-CSF Leukine Sargramostim,
Leukine®
Alzheimer's Disease (Phase 2) Genzyme, Sanofi Inflammation, Other, Unknown Other Bone Marrow Stimulation
GRF6019 Alzheimer's Disease (Phase 2) Alkahest, Inc., Grifols Biologicals Inc. Inflammation, Other, Unknown Other
GV1001 RIAVAXTM, Tertomotide Alzheimer's Disease (Phase 2) GemVax & KAEL Bio Other Immunotherapy (active) Pancreatic cancer (Korea)
LM11A-31-BHS LM11A-31 Alzheimer's Disease (Phase 2) PharmatrophiX Other Small Molecule
Liraglutide Victoza™,
Saxenda™
Alzheimer's Disease (Phase 2), Parkinson's Disease (Phase 2) Novo Nordisk A/S Other Other Diabetes, weight loss
Losartan Cozaar®,
MK0954
Alzheimer's Disease (Phase 2) Merck Other Small Molecule Hypertension, diabetic neuropathy
MSDC-0160 Mitoglitazone Alzheimer's Disease (Phase 2) Metabolic Solutions Development Company Other Small Molecule
Melatonin Alzheimer's Disease (Phase 2) Other Supplement, Dietary None
NIC5-15 Pinitol,
D-Pinitol
Alzheimer's Disease (Phase 2) Humanetics Pharmaceuticals Corporation Amyloid-Related, Other Small Molecule, Supplement, Dietary
Nasal Insulin Detemir,
Levemir,
Humulin,
Novolin
Alzheimer's Disease (Phase 2/3), Mild Cognitive Impairment (Phase 2), Parkinson's Disease (Phase 2), Multiple System Atrophy (Phase 2) Amyloid-Related, Other Small Molecule, Other Diabetes
Nicotinamide Enduramide,
Niacinamide,
Nicotinic acid amide,
Vitamin B3
Alzheimer's Disease (Phase 2) Other Small Molecule
Nilotinib Tasigna,
AMN107
Parkinson's Disease (Phase 2), Dementia with Lewy Bodies (Phase 2), Alzheimer's Disease (Phase 2) Novartis Pharmaceuticals Corporation Other Small Molecule Chronic myeloid leukemia
Piromelatine Neu-P11 Alzheimer's Disease (Phase 2) Neurim Pharmaceuticals Ltd. Other Neurotransmitters, Other Small Molecule
Repetitive Transcranial Magnetic Stimulation rTMS Alzheimer's Disease (Phase 2) Neuronix Ltd Other Procedural Intervention
Rilapladib SB-659032 Alzheimer's Disease (Phase 2) GlaxoSmithKline (GSK) Other Small Molecule
Riluzole Rilutek®,
RP 54274
Alzheimer's Disease (Phase 2), Parkinson's Disease (Discontinued), Amyotrophic Lateral Sclerosis (Approved), Huntington's Disease (Discontinued) Sanofi Other Neurotransmitters, Other Small Molecule Amyotrophic Lateral Sclerosis in many countries
SAR110894D Alzheimer's Disease (Phase 2) Sanofi Other Small Molecule
T3D-959 DB959 Alzheimer's Disease (Phase 2) T3D Therapeutics, Inc. Other Small Molecule
Telmisartan Micardis Alzheimer's Disease (Phase 2) Boehringer Ingelheim Other Small Molecule Hypertension
Valacyclovir Valtrex,
Valaciclovir,
256U87
Alzheimer's Disease (Phase 2) GlaxoSmithKline (GSK) Other Small Molecule Herpes virus outbreaks
Xanamem UE 2343 Alzheimer's Disease (Phase 2) Actinogen Medical Other Small Molecule