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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
ABT-957 Alzheimer's Disease (Phase 1) AbbVie Other Small Molecule
ALZ-801 NRM-8499, homotaurine, 3-APS Alzheimer's Disease (Phase 1) Alzheon Inc. Amyloid-Related Small Molecule
AZP2006 AZP-2006 Progressive Supranuclear Palsy (Phase 2), Alzheimer's Disease (Phase 1) AlzProtect Tau, Inflammation, Other Small Molecule
Allopregnanolone brexanolone,
3α-hydroxy-5α-pregnan-20-one,
3α,5α-tetrahydroprogesterone
Alzheimer's Disease (Phase 1) Other Neurotransmitters, Other Small Molecule
COR388 Alzheimer's Disease (Phase 1) Cortexyme, Inc. Other Small Molecule
Empagliflozin Jardiance,
BI-10773
Alzheimer's Disease (Phase 1) Boehringer Ingelheim, Eli Lilly & Co. Other Small Molecule Type 2 Diabetes, Cardiovascular disease
GC 021109 Alzheimer's Disease (Phase 1) GliaCure Inflammation Small Molecule
GLN-1062 Memogain Alzheimer's Disease (Phase 1) Galantos Pharma, Neurodyn Cholinergic System Small Molecule
GSK2647544 GSK-2647544 Alzheimer's Disease (Phase 1) GlaxoSmithKline (GSK) Cholesterol Small Molecule
Gemfibrozil Lopid,
Jezil,
Gen-Fibro
Alzheimer's Disease (Phase 1) Cholesterol Small Molecule Hyperlipidemia
HTL0018318 Alzheimer's Disease (Phase 1), Dementia with Lewy Bodies (Phase 2) Allergan plc, Sosei Heptares Cholinergic System Small Molecule
Inzomelid Alzheimer's Disease (Phase 1), Parkinson's Disease (Phase 1) Inflazome Ltd. Inflammation Small Molecule
JNJ-40346527 Edicotinib,
JNJ-527,
PRV-6527
Alzheimer's Disease (Phase 1) Janssen Inflammation Small Molecule
MW151 MW01-2-151SRM,
Minozac,
MW01-2-151WH,
compound 17
Alzheimer's Disease (Phase 1) ImmunoChem Therapeutics, LLC Inflammation Small Molecule
NDX-1017 Alzheimer's Disease (Phase 1) Athira Pharma Other Small Molecule
PU-AD Alzheimer's Disease (Phase 1) Samus Therapeutics Other Small Molecule
S-Equol Aus-131 Alzheimer's Disease (Phase 1) Ausio Pharmaceuticals, LLC Other Small Molecule
SUVN-G3031 Alzheimer's Disease (Phase 1) Suven Life Sciences Ltd Cholinergic System, Other Neurotransmitters Small Molecule