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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
ABT-957 Alzheimer's Disease (Phase 1) AbbVie Other Small Molecule
Allopregnanolone 3α,5α-tetrahydroprogesterone,
3α-hydroxy-5α-pregnan-20-one
Alzheimer's Disease (Phase 1) Other Neurotransmitters, Other Small Molecule
COR388 Alzheimer's Disease (Phase 1) Cortexyme, Inc. Other Small Molecule
DNL747 SAR 443060 Alzheimer's Disease (Phase 1), Amyotrophic Lateral Sclerosis (Phase 1) Denali Therapeutics Inc., Sanofi Inflammation Small Molecule
GC 021109 Alzheimer's Disease (Phase 1) GliaCure Inflammation Small Molecule
GLN-1062 Memogain Alzheimer's Disease (Phase 1) Galantos Pharma, Neurodyn Cholinergic System Small Molecule
GSK2647544 GSK-2647544 Alzheimer's Disease (Phase 1) GlaxoSmithKline (GSK) Cholesterol Small Molecule
HTL0018318 Alzheimer's Disease (Phase 1), Dementia with Lewy Bodies (Phase 2) Allergan plc, Sosei Heptares Cholinergic System Small Molecule
S-Equol Aus-131 Alzheimer's Disease (Phase 1) Ausio Pharmaceuticals, LLC Other Small Molecule
SUVN-G3031 Alzheimer's Disease (Phase 1) Suven Life Sciences Ltd Cholinergic System, Other Neurotransmitters Small Molecule
TPI 287 Alzheimer's Disease (Phase 1), CBD (Phase 1), Progressive Supranuclear Palsy (Phase 1) Cortice Biosciences Tau Small Molecule