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Name Synonyms FDA Status Company Target Type Therapy Type Approved
ACI-3024 Tau MorphomerTM Alzheimer's Disease (Phase 1), Other Tauopathy (Phase 1) AC Immune SA Tau Small Molecule
ACI-35 Alzheimer's Disease (Phase 1) AC Immune SA, Janssen Tau Immunotherapy (active)
AZP2006 AZP-2006 Progressive Supranuclear Palsy (Phase 2), Alzheimer's Disease (Phase 1) AlzProtect Tau, Inflammation, Other Small Molecule
BIIB076 NI-105,
6C5 huIgG1/l
Alzheimer's Disease (Phase 1) Biogen, Eisai Co., Ltd., Neurimmune Tau Immunotherapy (passive)
ISIS 814907
Alzheimer's Disease (Phase 1) Biogen, IONIS Pharmaceuticals Tau DNA/RNA-based
Bepranemab UCB0107 ,
UCB 0107 ,
Antibody D
Progressive Supranuclear Palsy (Phase 1), Alzheimer's Disease (Phase 1) Hoffmann-La Roche, UCB S.A. Tau Immunotherapy (passive)
E2814 Alzheimer's Disease (Phase 1) Eisai Co., Ltd. Tau Immunotherapy (passive)
LY3372689 Alzheimer's Disease (Phase 1) Tau Small Molecule
Lu AF87908 Alzheimer's Disease (Phase 1) H. Lundbeck Tau Immunotherapy (passive)
PNT001 Alzheimer's Disease (Phase 1), Traumatic Brain Injury (Phase 1) Pinteon Therapeutics Tau Immunotherapy (passive)