Therapeutics
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| Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
|---|---|---|---|---|---|---|
| ACI-3024 | Tau MorphomerTM | Alzheimer's Disease (Phase 1), Other Tauopathy (Phase 1) | AC Immune SA | Tau | Small Molecule | |
| ACI-35 | Alzheimer's Disease (Phase 1) | AC Immune SA, Janssen | Tau | Immunotherapy (active) | ||
| AZP2006 | AZP-2006 | Progressive Supranuclear Palsy (Phase 2), Alzheimer's Disease (Phase 1) | AlzProtect | Tau, Inflammation, Other | Small Molecule | |
| BIIB076 | NI-105, 6C5 huIgG1/l |
Alzheimer's Disease (Phase 1) | Biogen, Eisai Co., Ltd., Neurimmune | Tau | Immunotherapy (passive) | |
| BIIB080 | IONIS-MAPTRx, ISIS 814907 |
Alzheimer's Disease (Phase 1) | Biogen, IONIS Pharmaceuticals | Tau | DNA/RNA-based | |
| Bepranemab | UCB0107 , UCB 0107 , Antibody D |
Progressive Supranuclear Palsy (Phase 1), Alzheimer's Disease (Phase 1) | Hoffmann-La Roche, UCB S.A. | Tau | Immunotherapy (passive) | |
| E2814 | Alzheimer's Disease (Phase 1) | Eisai Co., Ltd. | Tau | Immunotherapy (passive) | ||
| LY3372689 | Alzheimer's Disease (Phase 1) | Tau | Small Molecule | |||
| Lu AF87908 | Alzheimer's Disease (Phase 1) | H. Lundbeck | Tau | Immunotherapy (passive) | ||
| PNT001 | Alzheimer's Disease (Phase 1), Traumatic Brain Injury (Phase 1) | Pinteon Therapeutics | Tau | Immunotherapy (passive) |