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Christian Haass on Striking Microgliosis in New APP Knock-in Mice

COMMENT This is a mouse model for amyloidosis, which, finally, is freely available for the entire research community. This is a big issue, considering that many experiments were blocked or slowed due to legal issues with mouse models. I think this is a great sign ...

Striking Microgliosis in New APP Knock-in Mice

RESEARCH NEWS 2021-02-06 Research News A new APP knock-in mouse has hit the scene. Researchers led by Pascal Sanchez, Denali Therapeutics, San Francisco, California, described the details in a paper posted to bioRxiv on January 20. They humanized the Aβ sequence in the mouse APP ...

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