COMMENT Chris Dobson has made a tremendous impact on the field of neurodegenerative disease. His findings that the formation of amyloid fibrils, as well as oligomer toxicity, are grossly sequence-independent have changed the way we think in this field. Chris has ...
COMMENT Chris was a truly exceptional scholar and scientist whose work transformed the study of protein-aggregation diseases, but also a remarkable person whose sharp wit, visionary leadership, and generosity were widely admired. He was a true pioneer, bringing ...
COMMENT I have known Chris Dobson for more than 25 years. He was one of my closest colleagues and a true friend. We got to know each other during a conference in England, and he spontaneously invited me and my wife, Manajit, to come to Oxford to discuss possible ...
Max-Planck-Institut für BiochemieGermany
JOB 2019-09-17 Employer UK Dementia Research Institute Principal Investigator Bart De Strooper Contact UK DRI HQ Head of HR Laura Allum, email@example.com, 020 3108 8137 Description The De Strooper lab, based in the UK DRI at UCL, is seeking an enthusiastic and ...
JOB 2019-09-17 Employer UK Dementia Research Institute, UCL Principal Investigator Bart De Strooper Contact UK DRI HQ Head of HR Laura Allum, firstname.lastname@example.org, 020 3108 8137 Description This is an excellent chance to work on high-impact, state-of-the-art projects in a ...
PAPER Miners JS, Kehoe PG, Love S, Zetterberg H, Blennow K
CSF evidence of pericyte damage in Alzheimer's disease is associated with markers of blood-brain barrier dysfunction and disease pathology.Alzheimers Res Ther. 2019 Sep 14;11(1):81. PubMed: 31521199
PAPER Coskuner O, Uversky VN
Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer's and Parkinson's diseases.Prog Mol Biol Transl Sci. 2019;166:145-223. Epub 2019 Jul 19 PubMed: 31521231
PAPER Soste M, Charmpi K, Lampert F, Gerez JA, van Oostrum M, Malinovska L, Boersema PJ, Prymaczok NC, Riek R, Peter M, Vanni S, Beyer A, Picotti P
Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity.Cell Syst. 2019 Aug 29; PubMed: 31521608
PAPER Camilleri A, Ghio S, Caruana M, Weckbecker D, Schmidt F, Kamp F, Leonov A, Ryazanov S, Griesinger C, Giese A, Cauchi RJ, Vassallo N31521630
PAPER Trumbore CN31521233
PAPER Randolph C
The Utility of Episodic Memory Cut-Off Scores for Inclusion in Clinical Trials for Early Symptomatic Alzheimer Disease.Am J Geriatr Psychiatry. 2019 Aug 19; PubMed: 31521488
PAPER Mack JE, Mesulam MM, Rogalski EJ, Thompson CK31521633