PAPER Akyol S, Yilmaz A, Oh KJ, Ugur Z, Aydas B, McGuinness B, Passmore P, Kehoe PG, Maddens M, Green BD, Graham SF
PAPER Kręcisz P, Czarnecka K, Szymański P
Physicochemical evaluation of new tetrahydroacridine and iodobenzoic acid hybrids as the next step in the design of potential drugs for treating Alzheimer's disease.Biomed Chromatogr. 2020 May 25;:e4906. PubMed: 32449534
PAPER Li D, Hagen C, Bui HH, Knopman D, Jack CR, Machulda M, Petersen RC, Mielke MM
Associations between cerebrospinal fluid total phosphatidylcholines, neurodegeneration, cognitive decline, and risk of mild cognitive impairment in the Mayo Clinic Study of Aging.Neurobiol Aging. 2020 Sep;93:52-54. Epub 2020 Apr 28 PubMed: 32450444
PAPER Lim B, Fowler C, Li QX, Rowe C, Dhiman K, Gupta VB, Masters CL, Doecke JD, Martins RN, Collins S, Diamandis EP
Decreased cerebrospinal fluid neuronal pentraxin receptor is associated with PET-Aβ load and cerebrospinal fluid Aβ in a pilot study of Alzheimer's disease.Neurosci Lett. 2020 Jul 13;731:135078. Epub 2020 May 23 PubMed: 32450185
PAPER Lara B, Carnes A, Dakterzada F, Benitez I, Piñol-Ripoll G
Neuropsychiatric symptoms and quality of life in Spanish patients with Alzheimer's disease during the COVID-19 lockdown.Eur J Neurol. 2020 May 25; PubMed: 32449791
PAPER Sohara K, Kiriyama T, Mizumura S, Ishiwata A, Yamazaki M, Kimura K, Kumita SI
Diagnostic utility and characteristics of CT-based attenuation correction in brain perfusion SPECT/CT in predicting the exacerbation of Alzheimer changes from mild cognitive impairment utilizing voxel-based statistical analysis in comparison with Chang'sAnn Nucl Med. 2020 Jul;34(7):502-511. Epub 2020 May 24 PubMed: 32449110
PAPER Tittelmeier J, Sandhof CA, Ries HM, Druffel-Augustin S, Mogk A, Bukau B, Nussbaum-Krammer C32449565
PAPER Vaiserman A, Koliada A, Lushchak O32450086
PAPER Rosas-Hernandez H, Cuevas E, Raymick JB, Robinson BL, Sarkar S
Impaired Amyloid Beta Clearance and Brain Microvascular Dysfunction are Present in the Tg-SwDI Mouse Model of Alzheimer's Disease.Neuroscience. 2020 May 23;440:48-55. PubMed: 32450297
PAPER Tao W, Sun J, Li X, Shao W, Pei J, Yang C, Wang W, Xu K, Wang J, Zhang Z
The Anterior-posterior Functional Connectivity Disconnection in the Elderly with Subjective Memory Impairment and Amnestic Mild Cognitive Impairment.Curr Alzheimer Res. 2020;17(4):373-381. PubMed: 32448103
PAPER Abo-Youssef AM, Khallaf WA, Khattab MM, Messiha BA
The anti-Alzheimer effect of telmisartan in a hyperglycemic ovariectomized rat model; role of central angiotensin and estrogen receptors.Food Chem Toxicol. 2020 May 22;142:111441. PubMed: 32450287
PAPER Baek YH, Kim HJ, Bae JH, Lee H, Oh IS, Kim WJ, Shin JY
Benzodiazepine-Related Cognitive Impairment or Dementia: A Signal Detection Study Using a Case/Non-Case Approach.Psychiatry Investig. 2020 Jun;17(6):587-595. Epub 2020 May 27 PubMed: 32450620
RESEARCH NEWS 2020-05-26 Research News In carriers of a pathogenic mutation in presenilin 1, plasma levels of the neurodegeneration marker neurofilament light (NfL) start to diverge from those in noncarriers more than two decades prior to when Alzheimer’s symptoms begin. That was ...
Charles Glabe on Alzheimer's Disease "Non-amyloidogenic" p3 Peptide Revisited: A Case for Amyloid-α.
COMMENT This is an interesting paper that reports that Aβ17-40 (also known as P3) forms β-sheet amyloid fibrils with properties like that of its longer sibling, Aβ1-40. Aβ variants at the carboxyl terminus and amino terminus have been extensively investigated ...