Ozgun Gokce

Klinikum der Universität München
Germany

Nico Dantuma on Alzheimer’s Field Loses Fred van Leeuwen, 71

COMMENT Our roads crossed during the first years of my postdoctoral project. In hindsight, I think that Fred and I probably started working around the same time on ubiquitin, Fred as a principal investigator in Amsterdam and me as a postdoctoral fellow in ...

Marcus O. W. Grimm, Tobias Hartmann on Alzheimer’s Field Loses Fred van Leeuwen, 71

COMMENT It is with great sadness and dismay that we heard of the death of our valued cooperation partner and friend Fred van Leeuwen, Ph.D. Fred has shaped Alzheimer's research for decades with innovative ideas and unique concepts, pushing science forward to ...

Daniel Michaelson on Would ApoE Make a Better Therapeutic Target Than Aβ?

COMMENT The Holtzman group's anti-ApoE antibody (HAE-4) recognizes human ApoE4 and ApoE3. This antibody binds specifically to non-lipidated human ApoE4 and ApoE3 and, when delivered to ApoE4-expressing mice, reduces Aβ deposition (Liao et al., 2018). These ...

PAPER Zarb Y, Sridhar S, Nassiri S, Utz SG, Schaffenrath J, Maheshwari U, Rushing EJ, Nilsson KP, Delorenzi M, Colonna M, Greter M, Keller A

Microglia control small vessel calcification via TREM2.

Sci Adv. 2021 Feb;7(9) Print 2021 Feb PubMed: 33637522

PAPER Pereira JV, Aung Thein MZ, Nitchingham A, Caplan GA

Delirium in older adults is associated with development of new dementia: a systematic review and meta-analysis.

Int J Geriatr Psychiatry. 2021 Feb 9; PubMed: 33638566

PAPER Weinberg R, Babagbemi K

Patient-Friendly Summary of the ACR Appropriateness Criteria: Dementia.

J Am Coll Radiol. 2021 Feb 23; PubMed: 33637458

PAPER Huber MK, Raichle C, Lingor P, Synofzik M, Borgmann S, Erber J, Tometten L, Rimili W, Dolff S, Wille K, Knauss S, Piepel C, Lanznaster J, Rieg S, Prasser F, Pilgram L, Spottke A, Klockgether T, Klein C, Hopfner F, Höglinger GU, LEOSS Study Group

Outcomes of SARS-CoV-2 Infections in Patients With Neurodegenerative Diseases in the LEOSS Cohort.

Mov Disord. 2021 Feb 27; PubMed: 33638915

PAPER Roshanbin S, Aniszewska A, Gumucio A, Masliah E, Erlandsson A, Bergström J, Ingelsson M, Ekmark-Lewén S

Age-related increase of alpha-synuclein oligomers is associated with motor disturbances in L61 transgenic mice.

Neurobiol Aging. 2021 Jan 28;101:207-220. PubMed: 33639338

PAPER Morató X, Garcia-Esparcia P, Argerich J, Llorens F, Zerr I, Paslawski W, Borràs E, Sabidó E, Petäjä-Repo UE, Fernández-Dueñas V, Ferrer I, Svenningsson P, Ciruela F

Ecto-GPR37: a potential biomarker for Parkinson's disease.

Transl Neurodegener. 2021 Feb 26;10(1):8. PubMed: 33637132

PAPER Lanteri P, Meola I, Canosa A, De Marco G, Lomartire A, Rinaudo MT, Albamonte E, Sansone VA, Lunetta C, Manera U, Vasta R, Moglia C, Calvo A, Origone P, Chiò A, Mandich P

The heterozygous deletion c.1509_1510delAG in exon 14 of FUS causes an aggressive childhood-onset ALS with cognitive impairment.

Neurobiol Aging. 2021 Feb 3; PubMed: 33637330

PAPER Shields LY, Li H, Nguyen K, Kim H, Doric Z, Garcia JH, Gill TM, Haddad D, Vossel K, Calvert M, Nakamura K

Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity.

J Biol Chem. 2021 Feb 24;:100469. PubMed: 33639169

PAPER Poddar MK, Banerjee S, Chakraborty A, Dutta D

Metabolic disorder in Alzheimer's disease.

Metab Brain Dis. 2021 Feb 27; PubMed: 33638805

PAPER Zhou X, Chen X, Hong T, Zhang M, Cai Y, Cui L

TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment.

Cell Mol Neurobiol. 2021 Feb 27; PubMed: 33638766

PAPER Altomare D, Caprioglio C, Assal F, Allali G, Mendes A, Ribaldi F, Ceyzeriat K, Martins M, Tomczyk S, Stampacchia S, Dodich A, Boccardi M, Chicherio C, Frisoni GB, Garibotto V

Diagnostic value of amyloid-PET and tau-PET: a head-to-head comparison.

Eur J Nucl Med Mol Imaging. 2021 Feb 27; PubMed: 33638661