Tharick Pascoal on Forget Typical Alzheimer's: AI Finds Four Types.

COMMENT In this important and well-powered tau PET study, Vogel, Hansson, and colleagues discovered four different patterns of tau deposition using machine learning. That individuals with these patterns had different cognitive profiles found in clinical practice ...

New Knock-In Mice Rapidly Accumulate Amyloid Plaques

RESEARCH NEWS 2021-05-07 Research News Researchers led by Takaomi Saido and Hiroki Sasaguri at the RIKEN Center for Brain Science, Wako, Japan, have developed a new, double knock-in model of amyloidosis. The mice produce human Aβ43 and Aβ42 in the brain, and they begin to deposit ...

PEERS Methods Club: Biofluid Biomarkers Edition- ISTAART Webinar

CONFERENCE 2021-06-01 00:00:00-2021-06-01 00:00:00 Webinar 01 June 2021 Time: 10:00 am ET Speakers: Wagner Brum, Marta Milà Alomà, James P. Quinn, Marc Suárez-Calvet, Charlotte Teunissen, Bianca Trombetta, and Henrik Zetterberg View Conference Website 0 ...

Daniel Cohen

New York State Psychiatric Institute/Columbia University Medical Center

NextGen Symposium on Protein Aggregation

CONFERENCE 2021-06-22 00:00:00-2021-06-22 00:00:00 Online Meeting 22 June 2021 A sub-meeting of the FASEB Protein Aggregation Conference. The symposium will highlight oral presentations from early career scientists in the field of protein aggregation and include a scientific development session. View ...


THERAPEUTICS Biogen IONIS Pharmaceuticals BIIB-078 IONIS-C9Rx DNA/RNA-based Other In September 2018, Biogen began a first-in-human Phase 1 in 114 adults who have ALS with C90ORF72 expansions. Participants must have a slow vital capacity greater than 50 percent of ...

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