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Dominic Walsh on Fog Beginning to Clear on Aβ-Degrading Enzymes?

COMMENT Aβ-degrading enzymes—many candidates, but few fit the bill This comment extends the news report filed directly from the meeting to provide a more detailed description of this emerging area. To date, a number of potential Aβ-degrading enzymes have been ...

Chris Exley on Fog Beginning to Clear on Aβ-Degrading Enzymes?

COMMENT This news report does not mention that the serine protease at the centre of the urokinase-plasminogen activator system, namely plasmin, is selective for Aβ 42 and in cleaving Aβ 42 prevents its aggregation into β-pleated sheet structures (see Exley and ...

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