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Alberto Lleo on Hemochromatosis as a Factor in AD

COMMENT I have read with interest the comment on HFE mutations and AD. Our group also postulated that a genetic defect in iron metabolism could be associated with a greater risk for AD. Therefore, we analyzed the two common HFE mutations and the Transferrin C2 ...

Michael Schlossmacher on Picking up the Pieces of Parkin

COMMENT Three principal issues arise from the literature reviewed by Dr. Wolozin and his comments: (1) an evolving concept that previously separated forms of parkinsonism actually present heterogeneity of one and the same Parkinson's disease (PD) syndrome; ...

Mark Gluck on Functional MRI Images Drug-Induced Memory Impairment

COMMENT Sperling and colleagues demonstrate how functional brain imaging, behavioral analyses, and pharmacological manipulations can be integrated within an interdisciplinary study of the pharmacology of memory and memory impairments. Their important contribution ...

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