Paul Coleman on Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition.
COMMENT This paper provides an additional aspect to the story of altered neuroplasticity in the AD brain. Although dendritic (e.g., Buell and Coleman, 1979) and GAP-43 data (Coleman et al., 1992) indicate reduced plasticity in AD brain, localized increased neurit