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Jürgen Götz on Tau Stymies Transport Through Neuron’s Nucleus

COMMENT I really liked this study, which elegantly combines work in human and transgenic tissue, in vitro and in primary cultures. The human brain and doxycycline rescue experiments in rTg4510 mice are especially compelling. I think the question (admittedly a ...

Diego Mastroeni on Tau Stymies Transport Through Neuron’s Nucleus

COMMENT Nucleocytoplasmic transport of molecules is essential for normal cell function. It is, in my opinion, the most basic and fundamental processes that initiate a cascade of events that leads to cellular aging and cell death. The mislocalization of molecules ...

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