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Lary Walker on Escort Service: P-Glycoprotein Ushers Aβ from Brain

COMMENT A recurring theme in the pathogenesis of diverse degenerative disorders is the accumulation of certain proteins in cells and tissues. Although many details remain to be ironed out, the pathogenic importance of cerebral Aβ accumulation in Alzheimer disease ...

Lary Walker on A seed for Alzheimer amyloid in the brain.

COMMENT In search of the “β Bang” The evidence strongly favors a crucial role of the peptide Aβ in the pathogenesis of Alzheimer’s disease (AD). In vitro studies have nicely illuminated the mechanics of polymerization and fibrillization of Aβ and other ...

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