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Terrence Town on Why Good Microglia Turn Bad—A Matter of Timing?

COMMENT The timely report by Hickman, Allison, and El Khoury presents an interesting interpretation of the interplay between microglia and cerebral amyloidosis. It has long been established that Tg2576 mice manifest microglial activation concomitant with Abeta ...

Terrence Town on Microglia—Medics or Meddlers in Dementia

COMMENT The report by El Khoury and colleagues shows that recruitment of macrophage-like cells to the brains of Tg2576 mice via Ccr2 plays an important role in limiting AD-like pathology. This is a very interesting finding and extends the work of Stalder et al. ...

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