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Rudy Tanzi on Presenilin Loss of Function—Plan B for AD?

COMMENT In the field of genetics, it is a rare and precious opportunity that we are afforded as scientists, when we can assess the effects of multiple mutations in multiple genes leading to common clinical and pathological disease phenotypes. We have this ...

Rudy Tanzi on An AD Gene Nugget on Chromosome 12?

COMMENT For a chromosome (chr 12) with only marginal genetic linkage signals, an unexpectedly large number of AD candidate genes have already been proposed over the past six years including A2M, LRP, OLR1, and LBP-1c. Now we need to add yet another, GAPD, which ...

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