Nikolaos K. Robakis on Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3 Kinase signalling mechanism.
COMMENT Nice paper. It contributes to emerging evidence that the PI3K/Akt/GSK-3 pathway is central to the regulation of tau phosphorylation. That presenilins regulate this pathway (through cadherin signaling) liks it to Alzheimer disease (AD) and provides further