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Rachael Neve on AD Cell Cycle Reentry—Early Rather Than Late

COMMENT Traditionally, neurons have been considered to be "locked" into the G0 phase of the cell cycle. The release of a differentiated cell from the resting G0 phase results in its entry into the first gap (G1) phase, during which the cell prepares for ...

Rachael Neve on SUMO-Wrestling with APP?

COMMENT This paper is groundbreaking in more than one respect. First of all, it presents a novel strategy for identifying modulators of APP processing. The authors screened 100,000 cDNAs from a human brain cDNA expression library. They began with 1,001 pools, ...

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