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Virgil Muresan on Huntingtin—Putting the Boot on Axonal Transport

COMMENT We would like to comment on the interesting results of the recent study by Morfini et al. (1). Kinesin-1, a major microtubule motor that transports cargo in the plus-end direction of microtubules, is a heterotetramer consisting of two microtubule-binding, ...

Virgil Muresan on APP Family: Clues to Function in Health and AD

COMMENT Yes, this is a great question: "Does APP have a function of its own (i.e., as a full-length protein), or does it function only through the polypeptides that are released through the complex processing of APP?" I am inclined to think that most of ...

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