Virgil Muresan on LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
COMMENT There is no question that the complex processing of amyloid-β precursor protein (APP), via at least two intensely studied pathways (α- and β-secretase cleavage) that are relevant to Alzheimer’s disease (AD), occurs during APP’s still insufficiently unders