Virgil Muresan on APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle.
COMMENT We read this paper by Szodorai et al. and found it interesting, especially with regard to the possibility that the small GTPase, Rab3A, could regulate sorting of APP into the cargo vesicle, and—possibly transport by kinesin-1. In fact, the idea that kines