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Elliott Mufson on The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.

COMMENT Rosch and colleagues in the May 17 issue of PNAS provide intriguing new data implicating p75NTR in activity-dependent synaptic plasticity. The authors use two strains of p75NTR mutants (p75NTRexonIV-/- and p75NTRexonII-/-) to investigate the emerging ...

Elliott Mufson on Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

COMMENT This is a most interesting and provocative study. It adds yet another wrinkle to the AD pathology cascade and suggests that cell cycle re-expression may be a major factor in the eventual cell death seen in AD. Data generated from our laboratory showing ...

Elliott Mufson on Huntingtin, BDNF, Neurodegeneration: Is Speed of the Essence?

COMMENT The findings of decreased BDNF transport in Huntington's disease, as well as the reports by the Brady and Goldstein groups are significant, as they support the hypothesis that various neurodegenerative disorders display impaired axonal transport ...

Elliott Mufson on Gender-specific nonrandom association between the alpha 1-antichymotrypsin and apolipoprotein E polymorphisms in the general population and its implication for the risk of Alzheimer's disease.

COMMENT Interesting emufson 0 ...

Elliott Mufson on Psychiatric correlates of MR deep white matter lesions in probable Alzheimer's disease.

COMMENT Interesting emufson 0 ...

Elliott Mufson on The inhibitory effects of beta-amyloid on glutamate and glucose uptakes by cultured astrocytes.

COMMENT Interesting. emufson 0 ...

Elliott Mufson on Cognitive enhancement therapy for Alzheimer's disease. The way forward.

COMMENT Useful. emufson 0 ...

Elliott Mufson on Mechanism of Alzheimer neurofibrillary degeneration and the formation of tangles.

COMMENT Interesting. emufson 0 ...

Elliott Mufson on Vascular variant of Alzheimer's disease characterized by severe plaque-like beta protein angiopathy.

COMMENT Interesting. emufson 0 ...

Elliott Mufson on Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells.

COMMENT Interesting emufson 0 ...

Elliott Mufson on Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

COMMENT Interesting. emufson 0 ...

Elliott Mufson on Potent inhibition of interleukin-6 expression in a human astrocytoma cell line by tenidap.

COMMENT Interesting. emufson 0 ...

Elliott Mufson on High density lipoprotein decreases beta-amyloid toxicity in cortical cell culture.

COMMENT Interesting study emufson 0 ...

Elliott Mufson on Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.

COMMENT Interesting emufson 0 ...

Elliott Mufson on Molecular forms of somatostatin-like immunoreactivity in the cerebrospinal fluid of patients with senile dementia of the Alzheimer type.

COMMENT Interesting. emufson 0 ...

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