Carl Cotman on Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients.
COMMENT Important 0 cwcotman
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COMMENT Important 0 cwcotman
COMMENT Interesting hypothesis [that in AD combined with cerebrovascular disease, the total plaque density makes a significant contribution to cognitive deficit, while NFTs do not.] 0 cwcotman
COMMENT Interesting 0 cwcotman
COMMENT This is an interesting paper which may indicate that A beta has a biphasic action on neurons, e.g. ACh metabolic versus apoptotic 0 cwcotman
COMMENT Interesting 0 cwcotman
COMMENT Reversibility is northy. 0 cwcotman
COMMENT New lead on subtype risk factors and their genetic basis. 0 cwcotman
COMMENT Interesting 0 cwcotman
COMMENT A key new lead. Specificity may be dependent on the PC12 line 0 cwcotman
COMMENT Interesting. See however Bonte et al, which reports an 86% sensitivity in autopsy confirmed cases 0 cwcotman Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients.
COMMENT Helps clarify a very complex literature 0 cwcotman
COMMENT Interesting 0 cwcotman
COMMENT A very interesting genetics paper 0 cwcotman
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