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Brandon Holmes on Could Contaminated Scalpels Seed Amyloidosis?

COMMENT Lauwers and colleagues present a helpful synopsis of the potential risk of human transmission of β-amyloid pathology by contaminated neurosurgical equipment and blood transfusions. The authors point out that the current evidence to support iatrogenic tran

Leslie Norins on Could Contaminated Scalpels Seed Amyloidosis?

COMMENT How strange that researchers focus on the patients, who get one brain operation each. Largely ignored is a possible risk to neurosurgeons, who all day are exposed to brain after brain, accompanied by glove nicks, sharps penetrations, and cautery smoke plu

Stéphane Haïk on Could Contaminated Scalpels Seed Amyloidosis?

COMMENT As underlined in this paper, to date, the risk of transmission associated with Aβ pathology during neurosurgery remains uncertain. Data are limited and inconclusive. In my opinion, they are by far insufficient to delay or forgo any necessary neurosurgery

Ronald Melki on Could Contaminated Scalpels Seed Amyloidosis?

COMMENT I’m not an expert on this precise topic. That said, we have considered this issue here in France and Professor Duyckaerts, myself, and others participated in a scientific committee that was convened on this topic in 2016. I was asked specifically to focus

Seth Love on Could Contaminated Scalpels Seed Amyloidosis?

COMMENT The evidence to date is that there may be a very small risk of transmission of pathogenic Aβ in the course of neurosurgical procedures, and that over several decades this can lead to the development of cerebral amyloid angiopathy. Neurosurgery carries ris

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