PAPER Du L, Suo S, Wang G, Jia H, Liu KJ, Zhao B, Liu Y
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PAPER Huang X, El-Sayed IH, Yi X, El-Sayed MA
Gold nanoparticles: catalyst for the oxidation of NADH to NAD(+).
J Photochem Photobiol B. 2005 Nov 1;81(2):76-83. Epub 2005 Aug 25 PubMed: 16125965CNM-Au8
THERAPEUTICS Clene Nanomedicine, Inc. Gold nanocrystals Other Metals Other In 2015-2016, Clene ran a placebo-controlled Phase 1 study of single and multiple doses of CNM-Au8. It enrolled 86 healthy volunteers, who received 15, 30, 60, or 90 mg single doses, or the sam
Taylor Howell
Leslie Norins on Earliest of Them All: Blood P-Tau231 Assay Flags Pre-Amyloid Alzheimer’s
COMMENT This remarkable paper seems to be opening a new horizon. Often such landmark reports raise more questions. For example, where is the detected tau coming from, and why? Is it the first sawdust visible as termites attack a majestic oak? And eventually the g
Charles Stromeyer on APOE Tied to Increased Susceptibility to SARS-CoV-2
COMMENT These studies did not examine brain capillary pericytes, which, unlike endothelial cells or other perivascular cell types, express ACE2, the receptor for SARS-CoV-2 (He et al., 2020). Within pericytes of APOE4 carriers, APOE and NFAT are selectively dysre
PAPER He L, Mäe MA, Muhl L, Sun Y, Pietilä R, Nahar K, Vázquez Liébanas E, Fagerlund MJ, Oldner A, Liu J, Genové G, Zhang L, Xie Y, Leptidis S, Mocci G, Stritt S, Osman A, Anisimov A, Hemanthakumar KA, Räsänen R, Mirabeau O, Hansson E, Björkegren J, Vanlandewijck M, Blomgren K, Mäkinen T, Peng XR, Arnold TD, Alitalo K, Lendahl U, Betsholtz C
Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 – implications for microvascular inflammation and hypercoagulopathy in COVID-19
bioRxiv, July 26, 2020.Gerald Pier
Harvard Medical SchoolBoston, United States
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