PAPER Guo Y, Zou G, Qi K, Jin J, Yao L, Pan Y, Xiong W
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PAPER Butler E, Mounsey A
Structural MRI for the Early Diagnosis of Alzheimer Disease in Patients with MCI.
Am Fam Physician. 2021 Mar 1;103(5):273-274. PubMed: 33630555PAPER Kovács RÁ, Vadászi H, Bulyáki É, Török G, Tóth V, Mátyás D, Kun J, Hunyadi-Gulyás É, Fedor FZ, Csincsi Á, Medzihradszky K, Homolya L, Juhász G, Kékesi KA, Józsi M, Györffy BA, Kardos J
Identification of Neuronal Pentraxins as Synaptic Binding Partners of C1q and the Involvement of NP1 in Synaptic Pruning in Adult Mice.
Front Immunol. 2020;11:599771. Epub 2021 Feb 8 PubMed: 33628204PAPER Zhou J, Hu L, Jiang Y, Liu L
A Correlation Analysis between SNPs and ROIs of Alzheimer's Disease Based on Deep Learning.
Biomed Res Int. 2021;2021:8890513. Epub 2021 Feb 9 PubMed: 33628827PAPER Levine DA, Gross AL, Briceño EM, Tilton N, Giordani BJ, Sussman JB, Hayward RA, Burke JF, Hingtgen S, Elkind MS, Manly JJ, Gottesman RF, Gaskin DJ, Sidney S, Sacco RL, Tom SE, Wright CB, Yaffe K, Galecki AT
Sex Differences in Cognitive Decline Among US Adults.
JAMA Netw Open. 2021 Feb 1;4(2):e210169. PubMed: 33630089Stranz VanWaldenberg
Madeleine Palser
Australia
Cristian Lasagna-Reeves on Would ApoE Make a Better Therapeutic Target Than Aβ?
COMMENT This paper by Monica Xiong and colleagues elegantly demonstrates how anti-human ApoE immunotherapy efficiently reduced vascular and parenchymal amyloid deposits in the 5XFAD model expressing human ApoE4, whereas an anti-Aβ immunotherapy had no effect on c
Would ApoE Make a Better Therapeutic Target Than Aβ?
RESEARCH NEWS 2021-02-26 Research News Although several anti-amyloid therapies in Alzheimer’s clinical trials melt away plaques, the process stresses blood vessels, causing tiny tears and fluid leakage into the brain. These morphological changes, dubbed amyloid-related imaging ab
Gary Landreth on Would ApoE Make a Better Therapeutic Target Than Aβ?
COMMENT This an impressive and important paper. Key to this study is the development of the HAE-4 anti-ApoE antibody and its specificity for poorly lipidated forms of ApoE, which are preferentially incorporated into amyloid plaques. The study is the quintessentia
Alzheimer’s Field Loses Fred van Leeuwen, 71
COMMUNITY NEWS 2021-02-26 Community News Fred van Leeuwen, professor at the Maastricht University in the Netherlands, passed away Wednesday, January 13. Van Leeuwen is best known for his discovery of a faulty transcription mechanism, dubbed “molecular misreading,” in the neurons o
Journal Club: Meet the Author- ISTAART Webinar
CONFERENCE 2021-04-15 00:00:00-2021-04-15 00:00:00 Webinar 15 April 2021 Alan Cronemberger Andrade will lead a conversation with Rachel Nosheny and Michael Weiner about the paper, Validation of Online Functional Measures in Cognitively Impaired Older Adults, published in Alzheimer's & Dementia. A
Tau Pathology in Down Syndrome and Alzheimer’s Disease- ISTAART Webinar
CONFERENCE 2021-04-14 00:00:00-2021-04-14 00:00:00 Webinar 14 April 2021 Speaker: Ann-Charlotte (Lotta) Granholm-Bentley, DDS, PhD, University of Denver Time: 12:00 noon ET View Conference Website 0
ISTAART Journal Club: Meet the Author
CONFERENCE 2021-04-01 00:00:00-2021-04-01 00:00:00 Webinar 01 April 2021 Lianne Reus will lead a conversation with Chengran Yang and Carlos Cruchaga about the paper, Genomic and Multi-Tissue Proteomic Integration for Understanding the Biology of Disease and Other Complex Traits, preprint. Greg Wheildon wi
ISTAART Journal Club Meet the Author
CONFERENCE 2021-03-18 00:00:00-2021-03-18 00:00:00 Webinar 18 March 2021 "Natasha de la Rosa-Rivera will lead a conversation with Tomohiro Nakamura and Stuart Lipton about the paper, Noncanonical Transnitrosylation Network Contributes to Synapse Loss in Alzheimer’s Disease, published in Science. Andr
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