Washington University School of MedicineSaint Louis, United States
PAPER Geurs TL, Hill EB, Lippold DM, French AR22209097
Brigham & Women's Hospital/Harvard Medical SchoolBoston, United States
COMMENT This interesting work raises questions such as how does the immune system surveil the CNS? One answer comes from a new paper in Cell led by Jonathan Kipnis, which shows immune cells in the meninge. When they study an MS mouse model, they find activated ...
PAPER Rustenhoven J, Drieu A, Mamuladze T, de Lima KA, Dykstra T, Wall M, Papadopoulos Z, Kanamori M, Salvador AF, Baker W, Lemieux M, Da Mesquita S, Cugurra A, Fitzpatrick J, Sviben S, Kossina R, Bayguinov P, Townsend RR, Zhang Q, Erdmann-Gilmore P, Smirnov I, Lopes MB, Herz J, Kipnis J33508229
COMMENT This elegant genetic study may have identified several important genes that may protect APOEε4-carriers from, or reduce APOEε2 carriers’ protection against, Alzheimer's disease. Both findings challenge our current understanding of APOE genotype as a ...
PAPER Goldstein MR, Poland GA, Graeber AC32339247
PAPER Zhang Q, Chen CZ, Swaroop M, Xu M, Wang L, Lee J, Wang AQ, Pradhan M, Hagen N, Chen L, Shen M, Luo Z, Xu X, Xu Y, Huang W, Zheng W, Ye Y32699847