PAPER Wie J, Liu Z, Song H, Tropea TF, Yang L, Wang H, Liang Y, Cang C, Aranda K, Lohmann J, Yang J, Lu B, Chen-Plotkin AS, Luk KC, Ren D33505021
PAPER Rezaei O, Nateghinia S, Estiar MA, Taheri M, Ghafouri-Fard S33508286
PAPER Zhang N, Yu X, Xie J, Xu H33507490
PAPER Jing Q, Zhang H, Sun X, Xu Y, Cao S, Fang Y, Zhao X, Li C33506048
PAPER Mahdi O, Baharuldin MT, Nor NH, Chiroma SM, Jagadeesan S, Moklas MA
The Neuroprotective Properties, Functions, and Roles of Cannabis sativa in Selected Diseases Related to the Nervous System.Cent Nerv Syst Agents Med Chem. 2021;21(1):20-38. PubMed: 33504317
PAPER Mahmoudi E, Lin P, Peterson MD, Meade MA, Tate DG, Kamdar N
Traumatic Spinal Cord Injury and Risk of Early and Late Onset Alzheimer's Disease and Related Dementia: Large Longitudinal Study.Arch Phys Med Rehabil. 2021 Jun;102(6):1147-1154. Epub 2021 Jan 27 PubMed: 33508336
PAPER Killoy KM, Pehar M, Harlan BA, Vargas MR
Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model.FASEB J. 2021 Feb;35(2):e21343. PubMed: 33508151
PAPER Zhang J, Liu R, Zhang D, Zhang Z, Zhu J, Xu L, Guo Y33508658
PAPER Saha J, Dean DN, Dhakal S, Stockmal KA, Morgan SE, Dillon KD, Adamo MF, Levites Y, Rangachari V
Biophysical characteristics of lipid-induced Aβ oligomers correlate to distinctive phenotypes in transgenic mice.FASEB J. 2021 Feb;35(2):e21318. PubMed: 33508158
PAPER Hallschmid M33506526
PAPER Minicucci J, Alfond M, Demuro A, Gerberry D, Latulippe J
Quantifying the dose-dependent impact of intracellular amyloid beta in a mathematical model of calcium regulation in xenopus oocyte.PLoS One. 2021;16(1):e0246116. Epub 2021 Jan 28 PubMed: 33508037
COMMENT This is an interesting paper by Wang et al. showing that APOE4 is a genetic modifier facilitating the direct infection of SARS-CoV-2 in human iPSC-derived neurons and astrocytes. I was surprised by this. Future studies should define if APOE4 causes this ...
COMMENT The history of Alzheimer’s Disease research demonstrates that getting a validated drug to market is incredibly difficult. So it is not surprising that all sorts of claims are made about alternatives, the “supplement hype” described here being one of them. ...
RESEARCH NEWS 2021-01-29 Research News Bouts of white-matter destruction in the brain and spinal cord are a hallmark of multiple sclerosis, but the inflammatory disease also ravages gray matter. Using a mouse model of cortical MS, researchers led by Doron Merkler at the ...
RESEARCH NEWS 2021-01-29 Research News Part 2 of a two-part series. Click here for Part 1. It turns out a person’s risk associated with ApoE4 goes beyond Alzheimer’s and vascular disease. This apolipoprotein allele can also worsen infections caused by certain viruses. One of ...