PAPER Wang WW, Zhang XR, Zhang ZR, Wang XS, Chen J, Chen SY, Xie CL

Effects of mGluR5 Antagonists on Parkinson's Patients With L-Dopa-Induced Dyskinesia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Front Aging Neurosci. 2018;10:262. Epub 2018 Sep 11 PubMed: 30271338

Asgeir Bjornsson

Cornelis Blauwendraat

Bethesda, United States

Alejandro Martínez Carrasco

Ph.D. student
London, United Kingdom

Dipraglurant

THERAPEUTICS 6-Fluoro-2-[4-(2-pyridinyl)-3-butyn-1-yl]imidazo[1,2-a]pyridine Addex Therapeutics ADX48621 Small Molecule Other Neurotransmitters Addex completed a Phase 2a trial for Parkinson’s Disease LID in 2012. Conducted in the U.S. and Europe, it enrolled 76 peopl

J.P.H. Burbach

University Medical Center Utrecht
Utrecht, Netherlands

Sopan Nangare

Research Scholar, ICMR, India
Shirpur, Dhule, India

Vrishali Salian

University of Minnesota
Minneapolis

Olivia Yanes

United States

Ozgun Gokce

Klinikum der Universität München
Germany

Nico Dantuma on Alzheimer’s Field Loses Fred van Leeuwen, 71

COMMENT Our roads crossed during the first years of my postdoctoral project. In hindsight, I think that Fred and I probably started working around the same time on ubiquitin, Fred as a principal investigator in Amsterdam and me as a postdoctoral fellow in Stockho

Marcus O. W. Grimm, Tobias Hartmann on Alzheimer’s Field Loses Fred van Leeuwen, 71

COMMENT It is with great sadness and dismay that we heard of the death of our valued cooperation partner and friend Fred van Leeuwen, Ph.D. Fred has shaped Alzheimer's research for decades with innovative ideas and unique concepts, pushing science forward to

Daniel Michaelson on Would ApoE Make a Better Therapeutic Target Than Aβ?

COMMENT The Holtzman group's anti-ApoE antibody (HAE-4) recognizes human ApoE4 and ApoE3. This antibody binds specifically to non-lipidated human ApoE4 and ApoE3 and, when delivered to ApoE4-expressing mice, reduces Aβ deposition (Liao et al., 2018). These f

PAPER Zarb Y, Sridhar S, Nassiri S, Utz SG, Schaffenrath J, Maheshwari U, Rushing EJ, Nilsson KP, Delorenzi M, Colonna M, Greter M, Keller A

Microglia control small vessel calcification via TREM2.

Sci Adv. 2021 Feb;7(9) Print 2021 Feb PubMed: 33637522

PAPER Huber MK, Raichle C, Lingor P, Synofzik M, Borgmann S, Erber J, Tometten L, Rimili W, Dolff S, Wille K, Knauss S, Piepel C, Lanznaster J, Rieg S, Prasser F, Pilgram L, Spottke A, Klockgether T, Klein C, Hopfner F, Höglinger GU, LEOSS Study Group

Outcomes of SARS-CoV-2 Infections in Patients with Neurodegenerative Diseases in the LEOSS Cohort.

Mov Disord. 2021 Apr;36(4):791-793. Epub 2021 Feb 27 PubMed: 33638915