PAPER van de Beek M, van Steenoven I, van der Zande JJ, Porcelijn I, Barkhof F, Stam CJ, Raijmakers PG, Scheltens P, Teunissen CE, van der Flier WM, Lemstra AW

Characterization of symptoms and determinants of disease burden in dementia with Lewy bodies: DEvELOP design and baseline results.

Alzheimers Res Ther. 2021 Feb 26;13(1):53. PubMed: 33637117

PAPER Watt JA, Veroniki AA, Tricco AC, Straus SE

Using a distribution-based approach and systematic review methods to derive minimum clinically important differences.

BMC Med Res Methodol. 2021 Feb 26;21(1):41. PubMed: 33637039

PAPER Haddad M, Hervé V, Ben Khedher MR, Rabanel JM, Ramassamy C

Glutathione: An Old and Small Molecule with Great Functions and New Applications in the Brain and in Alzheimer's Disease.

Antioxid Redox Signal. 2021 Aug 1;35(4):270-292. Epub 2021 May 25 PubMed: 33637005

PAPER Ye R, Locascio JJ, Goodheart AE, Quan M, Zhang B, Gomperts SN

Serum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study.

Parkinsonism Relat Disord. 2021 Apr;85:11-16. Epub 2021 Feb 17 PubMed: 33639572

PAPER Mazza MG, Palladini M, De Lorenzo R, Magnaghi C, Poletti S, Furlan R, Ciceri F, COVID-19 BioB Outpatient Clinic Study group, Rovere-Querini P, Benedetti F

Persistent psychopathology and neurocognitive impairment in COVID-19 survivors: Effect of inflammatory biomarkers at three-month follow-up.

Brain Behav Immun. 2021 May;94:138-147. Epub 2021 Feb 24 PubMed: 33639239

PAPER Ruppert MC, Greuel A, Freigang J, Tahmasian M, Maier F, Hammes J, van Eimeren T, Timmermann L, Tittgemeyer M, Drzezga A, Eggers C

The default mode network and cognition in Parkinson's disease: A multimodal resting-state network approach.

Hum Brain Mapp. 2021 Jun 1;42(8):2623-2641. Epub 2021 Feb 27 PubMed: 33638213

PAPER Jansson D, Dieriks VB, Rustenhoven J, Smyth LC, Scotter E, Aalderink M, Feng S, Johnson R, Schweder P, Mee E, Heppner P, Turner C, Curtis M, Faull R, Dragunow M

Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus.

Commun Biol. 2021 Feb 26;4(1):260. PubMed: 33637884

PAPER Baik K, Kim SM, Jung JH, Lee YH, Chung SJ, Yoo HS, Ye BS, Lee PH, Sohn YH, Kang SW, Kang SY

Donepezil for mild cognitive impairment in Parkinson's disease.

Sci Rep. 2021 Feb 26;11(1):4734. PubMed: 33637811

Shea Andrews on Massive GWAS Meta-Analysis Digs Up Trove of Alzheimer’s Genes

COMMENT The new genome-wide association study by Bellenguez et al. identified 75 risk loci associated with AD, of which 42 were novel. This effort was able to discover so many new loci primarily by increasing the sample size of the study, with the number of clini

Herpes Update—Virus Increases Dementia Risk in Sweden

RESEARCH NEWS 2021-02-28 Research News Epidemiological evidence of herpes involvement in dementia continues to accrue. The latest finding comes from a Swedish cohort of 530,000 people, all over 50 years old. In the February 14 Alzheimer’s & Dementia, researchers led by Hugo L

ALZgerm Challenge–No Winner, But Small Prizes to 8 Scientists

COMMUNITY NEWS 2021-02-28 Community News Three years ago, ALZgerm challenged researchers to find a single infectious agent responsible for Alzheimer’s disease. The bait was $1 million. Results were announced on February 23; alas, nobody took home the grand prize. Instead, ALZgerm

Nico Dantuma

Karolinska Institutet
Stockholm, Sweden

PAPER Sacco S, Paoletti M, Staffaroni AM, Kang H, Rojas J, Marx G, Goh SY, Luisa Mandelli M, Allen IE, Kramer JH, Bastianello S, Henry RG, Rosen HJ, Caverzasi E, Geschwind MD

Multimodal MRI staging for tracking progression and clinical-imaging correlation in sporadic Creutzfeldt-Jakob disease.

Neuroimage Clin. 2021;30:102523. Epub 2020 Dec 11 PubMed: 33636540

PAPER Tinaz S, Kamel S, Aravala SS, Sezgin M, Elfil M, Sinha R

Distinct neural circuits are associated with subclinical neuropsychiatric symptoms in Parkinson's disease.

J Neurol Sci. 2021 Apr 15;423:117365. Epub 2021 Feb 21 PubMed: 33636663

PAPER Terao Y, Tokushige SI, Inomata-Terada S, Fukuda H, Yugeta A, Ugawa Y

Deciphering the saccade velocity profile of progressive supranuclear palsy: A sign of latent cerebellar/brainstem dysfunction?

Clin Neurophysiol. 2021 Feb 3; PubMed: 33632587