PAPER Lowes H, Kurzawa-Akanbi M, Pyle A, Hudson G

Post-mortem ventricular cerebrospinal fluid cell-free-mtDNA in neurodegenerative disease.

Sci Rep. 2020 Sep 17;10(1):15253. PubMed: 32943697

PAPER Ikenoue T, Aprile FA, Sormanni P, Ruggeri FS, Perni M, Heller GT, Haas CP, Middel C, Limbocker R, Mannini B, Michaels TC, Knowles TP, Dobson CM, Vendruscolo M

A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer's disease.

Sci Rep. 2020 Sep 17;10(1):15280. PubMed: 32943652

PAPER Costa B, Manzoni C, Bernal-Quiros M, Kia DA, Aguilar M, Alvarez I, Alvarez V, Andreassen O, Anfossi M, Bagnoli S, Benussi L, Bernardi L, Binetti G, Blackburn D, Boada M, Borroni B, Bowns L, Bråthen G, Bruni AC, Chiang HH, Clarimon J, Colville S, Conidi ME, Cope TE, Cruchaga C, Cupidi C, Di Battista ME, Diehl-Schmid J, Diez-Fairen M, Dols-Icardo O, Durante E, Flisar D, Frangipane F, Galimberti D, Gallo M, Gallucci M, Ghidoni R, Graff C, Grafman JH, Grossman M, Hardy J, Hernández I, Holloway GJ, Huey ED, Illán-Gala I, Karydas A, Khoshnood B, Kramberger MG, Kristiansen M, Lewis PA, Lleó A, Madhan GK, Maletta R, Maver A, Menendez-Gonzalez M, Milan G, Miller B, Mol MO, Momeni P, Moreno-Grau S, Morris CM, Nacmias B, Nilsson C, Novelli V, Öijerstedt L, Padovani A, Pal S, Panchbhaya Y, Pastor P, Peterlin B, Piaceri I, Pickering-Brown S, Pijnenburg YA, Puca AA, Rainero I, Rendina A, Richardson AM, Rogaeva E, Rogelj B, Rollinson S, Rossi G, Rossmeier C, Rowe JB, Rubino E, Ruiz A, Sanchez-Valle R, Sando SB, Santillo AF, Saxon J, Scarpini E, Serpente M, Smirne N, Sorbi S, Suh E, Tagliavini F, Thompson JC, Trojanowski JQ, Van Deerlin VM, Van der Zee J, Van Broeckhoven C, van Rooij J, Van Swieten JC, Veronesi A, Vitale E, Waldö ML, Woodward C, Yokoyama J, Escott-Price V, Polke JM, Ferrari R, International FTD-Genetics Consortium

C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts.

Neurology. 2020 Dec 15;95(24):e3288-e3302. Epub 2020 Sep 17 PubMed: 32943482

PAPER Weston PS, Poole T, Nicholas JM, Toussaint N, Simpson IJ, Modat M, Ryan NS, Liang Y, Rossor MN, Schott JM, Ourselin S, Zhang H, Fox NC

Measuring cortical mean diffusivity to assess early microstructural cortical change in presymptomatic familial Alzheimer's disease.

Alzheimers Res Ther. 2020 Sep 17;12(1):112. PubMed: 32943095

PAPER Braun DJ, Dimayuga E, Morganti JM, Van Eldik LJ

Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer's disease.

J Neuroinflammation. 2020 Sep 17;17(1):274. PubMed: 32943069

PAPER Doytchinova I, Atanasova M, Salamanova E, Ivanov S, Dimitrov I

Curcumin Inhibits the Primary Nucleation of Amyloid-Beta Peptide: A Molecular Dynamics Study.

Biomolecules. 2020 Sep 15;10(9) PubMed: 32942739

PAPER Pérez M, Hernández F, Avila J

Protein Biomarkers for the Diagnosis of Alzheimer's Disease at Different Stages of Neurodegeneration.

Int J Mol Sci. 2020 Sep 15;21(18) PubMed: 32942527

PAPER Kim J, Kim M, Yoon JH

The tip-of-the-tongue phenomenon in older adults with subjective memory complaints.

PLoS One. 2020;15(9):e0239327. Epub 2020 Sep 18 PubMed: 32946498

PAPER Cooksey R, Kennedy J, Dennis MS, Escott-Price V, Lyons RA, Seaborne M, Brophy S

Proton pump inhibitors and dementia risk: Evidence from a cohort study using linked routinely collected national health data in Wales, UK.

PLoS One. 2020;15(9):e0237676. Epub 2020 Sep 18 PubMed: 32946449

PAPER Niu L, Li L, Yang S, Wang W, Ye C, Li H

Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington's disease transgenic mouse.

Cell Biosci. 2020;10:106. Epub 2020 Sep 11 PubMed: 32944220

Christopher Smith

Mauricetown, United States

Won-Jin Moon

Konkuk University Medical Center
Seoul, Korea, Republic of

PAPER Chatterjee M, Steffan JS, Lukacsovich T, Marsh JL, Agrawal N

Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila.

Exp Neurol. 2021 Apr;338:113463. Epub 2020 Sep 14 PubMed: 32941796

PAPER Zhou J, Zhao Y, Li Z, Zhu M, Wang Z, Li Y, Xu T, Feng D, Zhang S, Tang F, Yao J

miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.

Pharmacol Res. 2020 Oct;160:105197. Epub 2020 Sep 14 PubMed: 32942015

PAPER Khayer N, Mirzaie M, Marashi SA, Jalessi M

Rps27a might act as a controller of microglia activation in triggering neurodegenerative diseases.

PLoS One. 2020;15(9):e0239219. Epub 2020 Sep 17 PubMed: 32941527