6020 RESULTS
THERAPEUTICS Yumanity Therapeutics Small Molecule Other At the 2021 CTAD conference, Yumanity reported results of a Phase 1, single- and multiple-ascending-dose study of YTX-7739 in healthy volunteers. Beginning in October 2019, the single-dose study evaluated safety,
RESEARCH NEWS 2020-10-23 Research News Monochromator? Check. Second-generation spherical aberration corrector? Check. Titan Krios G3 electron microscope? Check. And not to forget the Falcon 3 direct electron detector. Check. It may sound like science fiction, but this new combina
CONFERENCE 2021-06-06 00:00:00-2021-06-11 00:00:00 Les Diablerets, Switzerland 06 June 2021 to 11 June 2021 New Date: 2023 View Conference Website 0
CONFERENCE 2021-07-03 00:00:00-2021-07-04 00:00:00 Castelldefels, Spain 03 July 2021 to 04 July 2021 New Date: 2023 View Conference Website 0
CONFERENCE 2021-07-04 00:00:00-2021-07-09 00:00:00 Castelldefels, Spain 04 July 2021 to 09 July 2021 New Date: 2023 View Conference Website 0
PAPER Davenport CM, Rajappa R, Katchan L, Taylor CR, Tsai MC, Smith CM, de Jong JW, Arnold DB, Lammel S, Kramer RH
CONFERENCE 2020-10-28 00:00:00-2020-10-28 00:00:00 Online Meeting 28 October 2020 Organizers: The Proteostasis Consortium led by Richard Morimoto, Ph.D., Northwestern University Speaker: Malene Hansen, PhD, Sanford Burnham Prebys Medical Discovery Institute, San Diego, California Meeting time: 12 PM EDT Z
PAPER Zhang K, Pintilie GD, Li S, Schmid MF, Chiu W
PAPER Herzik MA Jr
PAPER Nakane T, Kotecha A, Sente A, McMullan G, Masiulis S, Brown PM, Grigoras IT, Malinauskaite L, Malinauskas T, Miehling J, Uchański T, Yu L, Karia D, Pechnikova EV, de Jong E, Keizer J, Bischoff M, McCormack J, Tiemeijer P, Hardwick SW, Chirgadze DY, Murshudov G, Aricescu AR, Scheres SH
AlzforumUnited States
PAPER Yip KM, Fischer N, Paknia E, Chari A, Stark H
RESEARCH MODELS Summary App hu/hu mice carry a humanized Aβ sequence within the murine App gene. In this knock-in model, created using CRISPR/Cas9 technology, expression of App is driven by its natural promoter and is expected to show normal cell-type and temporal specif
RESEARCH MODELS Summary App hu/hu rats carry a humanized Aβ sequence within the rat App gene. In this knock-in model, created using CRISPR/Cas9 technology, expression of App is driven by its natural promoter and is expected to show normal cell-type and temporal specifici
RESEARCH MODELS Summary App hu/hu;Psen1M139T +/+ rats carry a humanized Aβ sequence within the rat App gene and the AD-linked M139T mutation in the rat Psen1 gene. These knock-in animals are homozygous for both humanized App and Psen1 M139T. Levels of APP and its metabol
