PAPER Kreher C, Favret J, Maulik M, Shin D

Lysosomal Functions in Glia Associated with Neurodegeneration.

Biomolecules. 2021 Mar 9;11(3) PubMed: 33803137

PAPER Lok HC, Kwok JB

The Role of White Matter Dysfunction and Leukoencephalopathy/Leukodystrophy Genes in the Aetiology of Frontotemporal Dementias: Implications for Novel Approaches to Therapeutics.

Int J Mol Sci. 2021 Mar 3;22(5) PubMed: 33802612

PAPER Orge L, Lima C, Machado C, Tavares P, Mendonça P, Carvalho P, Silva J, Pinto ML, Bastos E, Pereira JC, Gonçalves-Anjo N, Gama A, Esteves A, Alves A, Matos AC, Seixas F, Silva F, Pires I, Figueira L, Vieira-Pinto M, Sargo R, Pires MD

Neuropathology of Animal Prion Diseases.

Biomolecules. 2021 Mar 21;11(3) PubMed: 33801117

PAPER Barrio T, Vidal E, Betancor M, Otero A, Martín-Burriel I, Monzón M, Monleón E, Pumarola M, Badiola JJ, Bolea R

Evidence of p75 Neurotrophin Receptor Involvement in the Central Nervous System Pathogenesis of Classical Scrapie in Sheep and a Transgenic Mouse Model.

Int J Mol Sci. 2021 Mar 8;22(5) PubMed: 33800240

PAPER Ali T, Hannaoui S, Nemani S, Tahir W, Zemlyankina I, Cherry P, Shim SY, Sim V, Schaetzl HM, Gilch S

Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice.

Acta Neuropathol Commun. 2021 Apr 1;9(1):58. PubMed: 33795005

PAPER Brice NL, Schiffer HH, Monenschein H, Mulligan VJ, Page K, Powell J, Xu X, Cheung T, Burley JR, Sun H, Dickson L, Murphy ST, Kaushal N, Sheardown S, Lawrence J, Chen Y, Bartkowski D, Kanta A, Russo J, Hosea N, Dawson LA, Hitchcock SH, Carlton MB

Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease.

J Pharmacol Exp Ther. 2021 Jun;377(3):407-416. Epub 2021 Apr 1 PubMed: 33795395

PAPER Geloso MC, D'Ambrosi N

Microglial Pruning: Relevance for Synaptic Dysfunction in Multiple Sclerosis and Related Experimental Models.

Cells. 2021 Mar 20;10(3) PubMed: 33804596

PAPER Vavougios GD, Nday C, Pelidou SH, Gourgoulianis KI, Stamoulis G, Doskas T, Zarogiannis SG

Outside-in induction of the IFITM3 trafficking system by infections, including SARS-CoV-2, in the pathobiology of Alzheimer's disease.

Brain Behav Immun Health. 2021 Jul;14:100243. Epub 2021 Mar 26 PubMed: 33817671

PAPER Guyon A, Rousseau J, Bégin FG, Bertin T, Lamothe G, Tremblay JP

Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro.

Mol Ther Nucleic Acids. 2021 Jun 4;24:253-263. Epub 2021 Mar 1 PubMed: 33815938

PAPER Jiaranaikulwanitch J, Pandith H, Tadtong S, Thammarat P, Jiranusornkul S, Chauthong N, Nilkosol S, Vajragupta O

Novel Multifunctional Ascorbic Triazole Derivatives for Amyloidogenic Pathway Inhibition, Anti-Inflammation, and Neuroprotection.

Molecules. 2021 Mar 12;26(6) PubMed: 33809092

PAPER Yoon JH, Lee N, Youn K, Jo MR, Kim HR, Lee DS, Ho CT, Jun M

Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell.

Mar Drugs. 2021 Mar 15;19(3) PubMed: 33804171

PAPER Gaur P, Galkin M, Kurochka A, Ghosh S, Yushchenko DA, Shvadchak VV

Fluorescent Probe for Selective Imaging of α-Synuclein Fibrils in Living Cells.

ACS Chem Neurosci. 2021 Apr 21;12(8):1293-1298. Epub 2021 Apr 5 PubMed: 33819025

PAPER Chmielarz P, Domanskyi A

Alpha-synuclein preformed fibrils: a tool to understand Parkinson's disease and develop disease modifying therapy.

Neural Regen Res. 2021 Nov;16(11):2219-2221. PubMed: 33818501

PAPER Jia C, Cheng C, Li T, Chen X, Yang Y, Liu X, Li S, Le W

α-Synuclein Up-regulates Monoamine Oxidase A Expression and Activity via Trans-Acting Transcription Factor 1.

Front Aging Neurosci. 2021;13:653379. Epub 2021 Mar 17 PubMed: 33815093

PAPER Doppler K

Detection of Dermal Alpha-Synuclein Deposits as a Biomarker for Parkinson's Disease.

J Parkinsons Dis. 2021;11(3):937-947. PubMed: 33814464