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RESEARCH NEWS 2020-01-17 Research News Transgenic mice fail to capture many aspects of Alzheimer’s disease, and a new transcriptional study lays bare one reason. Brain cells in the two species, it turns out, respond quite differently to amyloidosis. In the January 13 Nature Medic
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RESEARCH MODELS Summary This is the second of two similar models designed to mimic BACE1 inhibition, in which researchers can control the timing of BACE1 deficiency. These conditional knockouts avoid the developmental effects of BACE1 deficiency that are seen in germline
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PAPER Bendikov-Bar I, Maor G, Filocamo M, Horowitz M
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PAPER Campos AC, Kikuchi DS, Paschoa AF, Kuroki MA, Fonoff ET, Hamani C, Pagano RL, Hernandes MS
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PAPER Vu L, An J, Kovalik T, Gendron T, Petrucelli L, Bowser R
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PAPER Lafon PA, Wang Y, Arango-Lievano M, Torrent J, Salvador-Prince L, Mansuy M, Mestre-Francès N, Givalois L, Liu J, Mercader JV, Jeanneteau F, Desrumaux C, Perrier V
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