PAPER Sathya S, Shanmuganathan B, Balasubramaniam B, Balamurugan K, Devi KP

Phytol loaded PLGA nanoparticles regulate the expression of Alzheimer's related genes and neuronal apoptosis against amyloid-β induced toxicity in Neuro-2a cells and transgenic Caenorhabditis elegans.

Food Chem Toxicol. 2020 Feb;136:110962. Epub 2019 Nov 14 PubMed: 31734340

PAPER Shakerin Z, Esfandiari E, Ghanadian M, Razavi S, Alaei H, Dashti G

Therapeutic effects of Cyperus rotundus rhizome extract on memory impairment, neurogenesis and mitochondria in beta-amyloid rat model of Alzheimer's disease.

Metab Brain Dis. 2020 Mar;35(3):451-461. Epub 2019 Nov 16 PubMed: 31734846

PAPER Forester BP, Rahman AT, Harper DG, Petrides G

Evolving Evidence for the Efficacy and Safety of ECT for Agitation in Alzheimer Disease.

Am J Geriatr Psychiatry. 2020 Feb;28(2):164-166. Epub 2019 Oct 24 PubMed: 31734085

PAPER Hoffman JL, Faccidomo S, Kim M, Taylor SM, Agoglia AE, May AM, Smith EN, Wong LC, Hodge CW

Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.

Int Rev Neurobiol. 2019;148:169-230. Epub 2019 Oct 23 PubMed: 31733664

PAPER Xiao B, He N, Wang Q, Cheng Z, Jiao Y, Haacke EM, Yan F, Shi F

Quantitative susceptibility mapping based hybrid feature extraction for diagnosis of Parkinson's disease.

Neuroimage Clin. 2019;24:102070. Epub 2019 Nov 5 PubMed: 31734535

Weiqun Liu

Blade Therapeutics, Inc
South San Francisco, United States

Renzo Mancuso on Cell-Specific Enhancer Atlas Centers AD Risk in Microglia. Again.

COMMENT This is an extraordinary study that provides a final piece of evidence for the causal involvement of microglia in Alzheimer’s disease. This work follows up a previous report from the same group, where the authors performed transcriptomic analysis of human ...

Andrea Crotti

Takeda
San Diego, United States

Maureen McLennon

Ruth Itzhaki on China Approves Seaweed Sugar as First New Alzheimer’s Drug in 17 Years

COMMENT The intriguing and encouraging results of the GV971 trial could be explained by an alternative—or perhaps additional—mechanism: the protective effect against AD might well be the consequence of the drug acting as an antiviral agent against HSV1, which has ...

PAPER Naesens L, Bonnafous P, Agut H, De Clercq E

Antiviral activity of diverse classes of broad-acting agents and natural compounds in HHV-6-infected lymphoblasts.

J Clin Virol. 2006 Dec;37 Suppl 1:S69-75. PubMed: 17276373

PAPER Harden EA, Falshaw R, Carnachan SM, Kern ER, Prichard MN

Virucidal activity of polysaccharide extracts from four algal species against herpes simplex virus.

Antiviral Res. 2009 Sep;83(3):282-9. Epub 2009 Jul 1 PubMed: 19576248

PAPER Saeki Y, Kato T, Okuda K

Inhibitory effects of funoran on the adherence and colonization of oral bacteria.

Bull Tokyo Dent Coll. 1996 May;37(2):77-92. PubMed: 9151580

PAPER Wang W, Wang SX, Guan HS

The antiviral activities and mechanisms of marine polysaccharides: an overview.

Mar Drugs. 2012 Dec 12;10(12):2795-816. PubMed: 23235364

Anietie Akpan

United Kingdom