PAPER Ko YH, Shim KY, Kim SK, Seo JY, Lee BR, Hur KH, Kim YJ, Kim SE, Do MH, Parveen A, Kim SY, Lee SY, Jang CG
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PAPER Martin GP, McDonald KR, Allsop D, Diggle PJ, Leroi I
Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis.
J Neurol. 2020 Jan;267(1):214-227. Epub 2019 Oct 15 PubMed: 31616991PAPER Spirgi S, Meyer A, Calabrese P, Gschwandtner U, Fuhr P
Effects of Cognitive Performance and Affective Status on Fatigue in Parkinson's Disease.
Dement Geriatr Cogn Dis Extra. 2019 Sep-Dec;9(3):344-351. Epub 2019 Sep 24 PubMed: 31616458PAPER Shah GV
Using MRI to Identify Supranuclear Palsy from Parkinson Disease and Dementia with Lewy Bodies.
Radiology. 2019 Dec;293(3):654-655. Epub 2019 Oct 15 PubMed: 31617819PAPER Saraon SK, Bernick C, Wint D, McConnell E
Screening for Adverse Drug Reactions in Dementia Patients on Cholinesterase Inhibitor Therapy.
J Am Geriatr Soc. 2020 Jan;68(1):216-218. Epub 2019 Oct 16 PubMed: 31617580PAPER Ke M, Chong CM, Su H
Using induced pluripotent stem cells for modeling Parkinson's disease.
World J Stem Cells. 2019 Sep 26;11(9):634-649. PubMed: 31616540PAPER Yurov YB, Vorsanova SG, Iourov IY
Chromosome Instability in the Neurodegenerating Brain.
Front Genet. 2019;10:892. Epub 2019 Sep 20 PubMed: 31616475Maurizio Severino
Rachel Bennett, Bradley Hyman on In Tauopathy, ApoE Destroys Neurons Via Microglia
COMMENT Both the Holtzman lab and our lab explored the role of microglia in mediating tau-induced neurodegenerative phenotypes in mice. Here, Shi et al. present exciting results of marked neuroprotection in a tau model after microglial ablation. In a different ta
Tau Natively Unstructured? Not Always, New Study Says
RESEARCH NEWS 2019-10-17 Research News Researchers for years thought that tau was a natively unstructured protein. Then how in the world do its supposedly disordered monomers give rise to the orderly stacks of tau molecules seen in tau fibrils? Using chemical cross-linkers to fre
PAPER Popov KI, Makepeace KA, Petrotchenko EV, Dokholyan NV, Borchers CH
Insight into the Structure of the "Unstructured" Tau Protein.
Structure. 2019 Nov 5;27(11):1710-1715.e4. Epub 2019 Oct 15 PubMed: 31628033PAPER Brodie NI, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH
Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations.
Sci Adv. 2017 Jul;3(7):e1700479. Epub 2017 Jul 7 PubMed: 28695211In Tauopathy, ApoE Destroys Neurons Via Microglia
RESEARCH NEWS 2019-10-17 Research News ApoE4 delivers a blow to neurons in mouse models of tauopathy but, according to a paper published October 10 in the Journal of Experimental Medicine, it only does so if mice have their microglia. Researchers led by David Holtzman at Washingt
TAK-341
THERAPEUTICS AstraZeneca Takeda Pharmaceutical Company MEDI1341 Immunotherapy (passive) alpha-synuclein In October 2017, Astra Zeneca began a Phase 1 single-ascending-dose study in 48 healthy volunteers age 18 to 65. Each volunteer was to receive a one-hour intravenou
Priscila Sanchez
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