PAPER Kawarabayashi T, Terakawa T, Takahashi A, Hasegawa H, Narita S, Sato K, Nakamura T, Seino Y, Hirohata M, Baba N, Ueda T, Harigaya Y, Kametani F, Maruyama N, Ishimoto M, St George-Hyslop P, Shoji M

Oral Immunization with Soybean Storage Protein Containing Amyloid-β 4-10 Prevents Spatial Learning Decline.

J Alzheimers Dis. 2019;70(2):487-503. PubMed: 31177217

PAPER Gomes FC, de Melo-Neto JS, Ferrari MF, Carlos CP, Goloni-Bertollo EM, Pavarino ÉC

Vitamin D3 increases the Caspase-3 p12, MTHFR, and P-glycoprotein reducing amyloid-β42 in the kidney of a mouse model for Down syndrome.

Life Sci. 2019 Aug 15;231:116537. Epub 2019 Jun 6 PubMed: 31176774

PAPER Cavendish JZ, Sarkar SN, Colantonio MA, Quintana DD, Ahmed N, White BA, Engler-Chiurazzi EB, Simpkins JW

Mitochondrial Movement and Number Deficits in Embryonic Cortical Neurons from 3xTg-AD Mice.

J Alzheimers Dis. 2019;70(1):139-151. PubMed: 31177221

PAPER Monacelli F, Martella L, Parodi MN, Odetti P, Fanelli F, Tabaton M

Frontal Variant of Alzheimer's Disease: A Report of a Novel PSEN1 Mutation.

J Alzheimers Dis. 2019;70(1):11-15. PubMed: 31177233

PAPER Eyler LT, Elman JA, Hatton SN, Gough S, Mischel AK, Hagler DJ, Franz CE, Docherty A, Fennema-Notestine C, Gillespie N, Gustavson D, Lyons MJ, Neale MC, Panizzon MS, Dale AM, Kremen WS

Resting State Abnormalities of the Default Mode Network in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.

J Alzheimers Dis. 2019;70(1):107-120. PubMed: 31177210

PAPER Li X, Hildebrandt A, Sommer W, Wilhelm O, Reuter M, Montag C, Zhou C

Cognitive Performance in Young APOE ε4 Carriers: A Latent Variable Approach for Assessing the Genotype-Phenotype Relationship.

Behav Genet. 2019 Sep;49(5):455-468. Epub 2019 Jun 8 PubMed: 31177340

PAPER Pinto C, Medinas DB, Fuentes-Villalobos F, Maripillán J, Castro AF, Martínez AD, Osses N, Hetz C, Henríquez JP

β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation.

Neurobiol Dis. 2019 Oct;130:104497. Epub 2019 Jun 7 PubMed: 31176720

PAPER He H, Huang W, Wang R, Lin Y, Guo Y, Deng J, Deng H, Zhu Y, Allen EG, Jin P, Duan R

Amyotrophic Lateral Sclerosis-associated GGGGCC repeat expansion promotes Tau phosphorylation and toxicity.

Neurobiol Dis. 2019 Oct;130:104493. Epub 2019 Jun 6 PubMed: 31176718

PAPER Koza P, Beroun A, Konopka A, Górkiewicz T, Bijoch L, Torres JC, Bulska E, Knapska E, Kaczmarek L, Konopka W

Neuronal TDP-43 depletion affects activity-dependent plasticity.

Neurobiol Dis. 2019 Oct;130:104499. Epub 2019 Jun 6 PubMed: 31176717

PAPER van de Beek M, van Steenoven I, Ramakers IH, Aalten P, Koek HL, Olde Rikkert MG, Manniën J, Papma JM, de Jong FJ, Lemstra AW, van der Flier WM

Trajectories and Determinants of Quality of Life in Dementia with Lewy Bodies and Alzheimer's Disease.

J Alzheimers Dis. 2019;70(2):389-397. PubMed: 31177218

Betty Hansen

Zephyrhills, United States

Anna Vasilevskaya

Toronto, Canada

James Wallace on Serial PET Nails It: Preclinical AD Means Amyloid, Tau, then Cognitive Decline

COMMENT This paper provides a crucial window into the pathology of AD. The results appear to imply that tau is more directly related to cognitive decline than Aβ, and that developing therapeutics directed at abrogating tau might more likely to impede dementia ...

PAPER Fu X, Shrestha S, Sun M, Wu Q, Luo Y, Zhang X, Yin J, Ni H

Microstructural White Matter Alterations in Mild Cognitive Impairment and Alzheimer's Disease: Study Based on Neurite Orientation Dispersion and Density Imaging (NODDI).

Clin Neuroradiol. 2019 Jun 7; PubMed: 31175374

PAPER Vatanabe IP, Manzine PR, Cominetti MR

Historic concepts of dementia and Alzheimer's disease: From ancient times to the present.

Rev Neurol (Paris). 2019 Jun 4; PubMed: 31174886