PAPER Byers S, Buchler IP, DePasquale M, Rowley HL, Kulkarni RS, Pinder L, Kolobova A, Li C, Au V, Akuma D, Zhang G, Wei H, Cheetham SC, Barrow JC, Carr GV
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Eunsun Jang
Lars Lannfelt, Per-Ola Freskgård on Molecular Transport Vehicle Shuttles Therapies into Brain
COMMENT Monoclonal antibodies are very interesting as therapeutics, also for Alzheimer’s disease. They can be made highly specific for their target, which is an obvious advantage when focusing on aggregating proteins where not all forms are toxic. However, one pr
Shiny SEQUIN: New Technique Counts Synapses Over Large Brain Volumes
RESEARCH NEWS 2020-06-01 Research News Synapses are central in Alzheimer’s disease, but they are hard to study. The microscopic techniques that offer a glimpse at these tiny structures require expensive equipment and laborious ultra-sectioning of brain tissue, and cover only very
PAPER Montemiglio LC, Testi C, Ceci P, Falvo E, Pitea M, Savino C, Arcovito A, Peruzzi G, Baiocco P, Mancia F, Boffi A, des Georges A, Vallone B
Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.
Nat Commun. 2019 Mar 8;10(1):1121. PubMed: 30850661PAPER Gregor I, Enderlein J
Image scanning microscopy.
Curr Opin Chem Biol. 2019 Aug;51:74-83. Epub 2019 Jun 13 PubMed: 31203139Marcia Ratner on Simulating Tangle Spread Along Axons, Scientists Predict Tau PET Patterns
COMMENT These are exciting findings. It has been suggested previously that tau pathology begins in locus coeruleus, from which it spreads in a connectome‐dependent pattern during the progression of Alzheimer's from the subclinical to clinically overt stages
PAPER Yang C, Gao Y
Mesencephalic astrocyte-derived neurotrophic factor: A treatment option for parkinson's disease.
Front Biosci (Landmark Ed). 2020 Jun 1;25:1718-1731. PubMed: 32472754PAPER Facchinetti R, Valenza M, Bronzuoli MR, Menegoni G, Ratano P, Steardo L, Campolongo P, Scuderi C
Looking for a Treatment for the Early Stage of Alzheimer's Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin.
Int J Mol Sci. 2020 May 27;21(11) PubMed: 32471239PAPER Chetia P, Mazumder MK, Mahanta S, De B, Dutta Choudhury M
A novel phytochemical from Dipteris wallichii inhibits human β-secretase 1: Implications for the treatment of Alzheimer's disease.
Med Hypotheses. 2020 Oct;143:109839. Epub 2020 May 18 PubMed: 32473508PAPER Chen YR, Lai PL, Chien Y, Lee PH, Lai YH, Ma HI, Shiau CY, Wang KC
Improvement of Impaired Motor Functions by Human Dental Exfoliated Deciduous Teeth Stem Cell-Derived Factors in a Rat Model of Parkinson's Disease.
Int J Mol Sci. 2020 May 27;21(11) PubMed: 32471263PAPER Kawahata I, Fukunaga K
Degradation of Tyrosine Hydroxylase by the Ubiquitin-Proteasome System in the Pathogenesis of Parkinson's Disease and Dopa-Responsive Dystonia.
Int J Mol Sci. 2020 May 27;21(11) PubMed: 32471089PAPER Panek WK, Gruen ME, Murdoch DM, Marek RD, Stachel AF, Mowat FM, Saker KE, Olby NJ
Plasma Neurofilament Light Chain as a Translational Biomarker of Aging and Neurodegeneration in Dogs.
Mol Neurobiol. 2020 Jul;57(7):3143-3149. Epub 2020 May 30 PubMed: 32472519PAPER Yun Y, Ha Y
CRISPR/Cas9-Mediated Gene Correction to Understand ALS.
Int J Mol Sci. 2020 May 27;21(11) PubMed: 32471232PAPER Ahmed GA, El Hotaby W, Abbas L, Sherif HH, Kamel G, Khalil SK
Synchrotron Fourier transform infrared microspectroscopy (sFTIRM) analysis of Al-induced Alzheimer's disease in rat brain cortical tissue.
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Oct 5;239:118421. Epub 2020 May 5 PubMed: 32473558Current Filters
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