PAPER Schnöder L, Gasparoni G, Nordström K, Schottek A, Tomic I, Christmann A, Schäfer KH, Menger MD, Walter J, Fassbender K, Liu Y
PAPER Byers S, Buchler IP, DePasquale M, Rowley HL, Kulkarni RS, Pinder L, Kolobova A, Li C, Au V, Akuma D, Zhang G, Wei H, Cheetham SC, Barrow JC, Carr GV
Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility.Psychopharmacology (Berl). 2020 Sep;237(9):2695-2707. Epub 2020 May 30 PubMed: 32474681
COMMENT Monoclonal antibodies are very interesting as therapeutics, also for Alzheimer’s disease. They can be made highly specific for their target, which is an obvious advantage when focusing on aggregating proteins where not all forms are toxic. However, one ...
RESEARCH NEWS 2020-06-01 Research News Synapses are central in Alzheimer’s disease, but they are hard to study. The microscopic techniques that offer a glimpse at these tiny structures require expensive equipment and laborious ultra-sectioning of brain tissue, and cover only very ...
PAPER Montemiglio LC, Testi C, Ceci P, Falvo E, Pitea M, Savino C, Arcovito A, Peruzzi G, Baiocco P, Mancia F, Boffi A, des Georges A, Vallone B30850661
PAPER Gregor I, Enderlein J31203139
COMMENT These are exciting findings. It has been suggested previously that tau pathology begins in locus coeruleus, from which it spreads in a connectome‐dependent pattern during the progression of Alzheimer's from the subclinical to clinically overt stages ...
PAPER Lesage S, Lunati A, Houot M, Romdhan SB, Clot F, Tesson C, Mangone G, Toullec BL, Courtin T, Larcher K, Benmahdjoub M, Arezki M, Bouhouche A, Anheim M, Roze E, Viallet F, Tison F, Broussolle E, Emre M, Hanagasi H, Bilgic B, Tazir M, Djebara MB, Gouider R, Tranchant C, Vidailhet M, Le Guern E, Corti O, Mhiri C, Lohmann E, Singleton A, Corvol JC, Brice A, French Parkinson disease Genetics Study Group (PDG)32472966
PAPER Uddin MS, Rahman MA, Kabir MT, Behl T, Mathew B, Perveen A, Barreto GE, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM
Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.IUBMB Life. 2020 May 30; PubMed: 32472959
PAPER Wesselman LM, van Lent DM, Schröder A, van de Rest O, Peters O, Menne F, Fuentes M, Priller J, Spruth EJ, Altenstein S, Schneider A, Fließbach K, Roeske S, Wolfsgruber S, Kleineidam L, Spottke A, Pross V, Wiltfang J, Vukovich R, Schild AK, Düzel E, Metzger CD, Glanz W, Buerger K, Janowitz D, Perneczky R, Tatò M, Teipel S, Kilimann I, Laske C, Buchmann M, Ramirez A, Sikkes SA, Jessen F, van der Flier WM, Wagner M
Dietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer's disease.Eur J Nutr. 2020 May 29; PubMed: 32472387
PAPER Abrahamson EE, Stehouwer JS, Vazquez AL, Huang GF, Mason NS, Lopresti BJ, Klunk WE, Mathis CA, Ikonomovic MD32471773
PAPER Kumari E, Li K, Yang Z, Zhang T
Tacrine accelerates spatial long-term memory via improving impaired neural oscillations and modulating GAD isomers including neuro-receptors in the hippocampus of APP/PS1 AD mice.Brain Res Bull. 2020 Aug;161:166-176. Epub 2020 May 28 PubMed: 32473192
PAPER Facchinetti R, Valenza M, Bronzuoli MR, Menegoni G, Ratano P, Steardo L, Campolongo P, Scuderi C
Looking for a Treatment for the Early Stage of Alzheimer's Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin.Int J Mol Sci. 2020 May 27;21(11) PubMed: 32471239
PAPER Chen YR, Lai PL, Chien Y, Lee PH, Lai YH, Ma HI, Shiau CY, Wang KC