PAPER Kakati T, Bhattacharyya DK, Barah P, Kalita JK

Comparison of Methods for Differential Co-expression Analysis for Disease Biomarker Prediction.

Comput Biol Med. 2019 Oct;113:103380. Epub 2019 Aug 10 PubMed: 31415946

PAPER Yamazaki T, Inui Y, Ichihara T, Uno M, Ota S, Toyoda A, Ishiguro M, Kato T, Ito K, Toyama H

Clinical utility of the normal database of 123I-iodoamphetamine brain perfusion single photon emission computed tomography for statistical analysis using computed tomography-based attenuation correction: a multicenter study.

Ann Nucl Med. 2019 Nov;33(11):835-841. Epub 2019 Aug 14 PubMed: 31414335

PAPER Gomes LA, Hipp SA, Rijal Upadhaya A, Balakrishnan K, Ospitalieri S, Koper MJ, Largo-Barrientos P, Uytterhoeven V, Reichwald J, Rabe S, Vandenberghe R, von Arnim CA, Tousseyn T, Feederle R, Giudici C, Willem M, Staufenbiel M, Thal DR

Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein.

Acta Neuropathol. 2019 Dec;138(6):913-941. Epub 2019 Aug 14 PubMed: 31414210

PAPER Xu Y, Zhang Z, Jiang X, Chen X, Wang Z, Alsulami H, Qin HL, Tang W

Discovery of δ-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies.

Eur J Med Chem. 2019 Nov 1;181:111598. Epub 2019 Aug 6 PubMed: 31415981

PAPER Riquelme A, Valdés-Tovar M, Ugalde O, Maya-Ampudia V, Fernández M, Mendoza-Durán L, Rodríguez-Cárdenas L, Benítez-King G

Potential Use of Exfoliated and Cultured Olfactory Neuronal Precursors for In Vivo Alzheimer's Disease Diagnosis: A Pilot Study.

Cell Mol Neurobiol. 2020 Jan;40(1):87-98. Epub 2019 Aug 14 PubMed: 31414299

PAPER Marín-Lahoz J, Sampedro F, Martinez-Horta S, Pagonabarraga J, Kulisevsky J

Depression as a Risk Factor for Impulse Control Disorders in Parkinson Disease.

Ann Neurol. 2019 Nov;86(5):762-769. Epub 2019 Aug 31 PubMed: 31415102

PAPER Lim B, Tsolaki M, Soosaipillai A, Brown M, Zilakaki M, Tagaraki F, Fotiou D, Koutsouraki E, Grosi E, Prassas I, Diamandis EP

Liquid biopsy of cerebrospinal fluid identifies neuronal pentraxin receptor (NPTXR) as a biomarker of progression of Alzheimer's disease.

Clin Chem Lab Med. 2019 Nov 26;57(12):1875-1881. PubMed: 31415236

PAPER Jiang AA, Longardner K, Dickson D, Sell R

Gerstmann-Sträussler-Scheinker syndrome misdiagnosed as conversion disorder.

BMJ Case Rep. 2019 Aug 13;12(8) PubMed: 31413052

PAPER Fão L, Mota SI, Rego AC

Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases.

Ageing Res Rev. 2019 Sep;54:100942. Epub 2019 Aug 12 PubMed: 31415806

PAPER Chang S, Guo X, Li G, Zhang X, Li J, Jia Y, Nie K

Acupuncture promotes expression of Hsp84/86 and delays brain ageing in SAMP8 mice.

Acupunct Med. 2019 Dec;37(6):340-347. Epub 2019 Aug 15 PubMed: 31412703

PAPER Mancuso R, Sicurella M, Agostini S, Marconi P, Clerici M

Herpes simplex virus type 1 and Alzheimer's disease: link and potential impact on treatment.

Expert Rev Anti Infect Ther. 2019 Sep;17(9):715-731. Epub 2019 Aug 23 PubMed: 31414935

PAPER Growcott EJ, Bamba D, Galarneau JR, Leonard VH, Schul W, Stein D, Osborne CS

The effect of P38 MAP kinase inhibition in a mouse model of influenza.

J Med Microbiol. 2018 Mar;67(3):452-462. Epub 2018 Jan 24 PubMed: 29458547

Yadong Huang on ApoE4 Glia Bungle Lipid Processing, Mess with the Matrisome

COMMENT This is an interesting and comprehensive whole-transcriptome study of APOE4 and Alzheimer’s disease (AD), using human iPSC-derived brain cells, mouse brain cells, and cell-type deconvoluted transcriptomic data from postmortem AD brains. An important ...

Sonal Agrawal

Rush University medical Center
Chicago, United States

Guojun Bu on ApoE4 Glia Bungle Lipid Processing, Mess with the Matrisome

COMMENT This is an exciting study demonstrating that APOE4 is associated with dysregulation of cholesterol homeostasis in human but not mouse astrocytes and microglia. Although such an association was implicated in previous studies, including those addressing ...