PAPER Haaksma ML, Rizzuto D, Leoutsakos JS, Marengoni A, Tan EC, Olde Rikkert MG, Fratiglioni L, Melis RJ, Calderón-Larrañaga A
PAPER Świetlik D, Białowąs J, Moryś J, Klejbor I, Kusiak A
Computer Modeling of Alzheimer's Disease-Simulations of Synaptic Plasticity and Memory in the CA3-CA1 Hippocampal Formation Microcircuit.Molecules. 2019 May 17;24(10) PubMed: 31108977
Monterrey , Mexico
The University of ChicagoChicago, United States
Washington, United States
PAPER Lalonde R, Strazielle C
PS1 knockin mice with the Japanese I213T mutation: effects on exploratory activity, motor coordination, and spatial learning.Behav Brain Res. 2005 Jul 30;162(2):182-90. PubMed: 15908021
CONFERENCE COVERAGE SERIES Antisense Oligonucleotides: Can They Take on ALS, SMA, Prions? Drug Reported to Help Alzheimer’s Patients Sleep Better American Academy of Neurology 2019 Annual Meeting ...
CONFERENCE COVERAGE 2019-05-22 Conference Coverage At the American Academy of Neurology’s 71st Annual Meeting, held May 4–10 in Philadelphia, researchers showcased their latest data on antisense oligonucleotides (ASOs). These short, synthetic, single-stranded oligodeoxynucleotides bind ...
RESEARCH NEWS 2019-05-22 Research News Two studies offer new potential ways of quelling the neuron-killing rampage of the C9ORF72 hexanucleotide expansion, the biggest genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). In one, a mouse model ...
University of South FloridaTampa, United States
PAPER Goodman LD, Prudencio M, Kramer NJ, Martinez-Ramirez LF, Srinivasan AR, Lan M, Parisi MJ, Zhu Y, Chew J, Cook CN, Berson A, Gitler AD, Petrucelli L, Bonini NM
Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD.Nat Neurosci. 2019 Jun;22(6):863-874. Epub 2019 May 20 PubMed: 31110321