PAPER Gorges M, Kunz MS, Müller HP, Liepelt-Scarfone I, Storch A, Dodel R, Hilker-Roggendorf R, LANDSCAPE Consortium, Berg D, Kalbe E, Braak H, Del Tredici K, Baudrexel S, Huppertz HJ, Kassubek J

Longitudinal brain atrophy distribution in advanced Parkinson's disease: What makes the difference in "cognitive status" converters?

Hum Brain Mapp. 2020 Apr 15;41(6):1416-1434. Epub 2019 Dec 2 PubMed: 31789477

PAPER Jia X, Wang Z, Yang T, Li Y, Gao S, Wu G, Jiang T, Liang P

Entorhinal Cortex Atrophy in Early, Drug-naive Parkinson's Disease with Mild Cognitive Impairment.

Aging Dis. 2019 Dec;10(6):1221-1232. PubMed: 31788334

PAPER Martínez-Ramírez D, Cervantes-Arriaga A, Garza-Brambila D, Salinas-Barboza K, Isaís-Millán S, Anaya-Escamilla A, Velázquez-Ávila ES, Banegas-Lagos A, Gonzalez-Cantú A, Rodríguez-Violante M

Factores asociados con deterioro cognitivo en una cohorte mexicana multicéntrica de Parkinson: estudio transversal comparativo.

Gac Med Mex. 2019;155(6):602-607. PubMed: 31787767

PAPER Liu Y, Gui Y, Hu J, Liang S, Mo S, Zhou Y, Li Y, Zhou F, Xu J

Attention/memory complaint is correlated with motor speech disorder in Parkinson's disease.

BMC Neurol. 2019 Dec 1;19(1):309. PubMed: 31787082

PAPER Martínez-Horta S, Horta-Barba A, Perez-Perez J, Antoran M, Pagonabarraga J, Sampedro F, Kulisevsky J

Impaired face-like object recognition in premanifest Huntington's disease.

Cortex. 2020 Feb;123:162-172. Epub 2019 Nov 13 PubMed: 31794910

PAPER Yambire KF, Rostosky C, Watanabe T, Pacheu-Grau D, Torres-Odio S, Sanchez-Guerrero A, Senderovich O, Meyron-Holtz EG, Milosevic I, Frahm J, West AP, Raimundo N

Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo.

Elife. 2019 Dec 3;8 PubMed: 31793879

PAPER Shin SK, Yoo JM, Li FY, Baek SY, Kim MR

Mulberry fruit improves memory in scopolamine-treated mice: role of cholinergic function, antioxidant system, and TrkB/Akt signaling.

Nutr Neurosci. 2019 Dec 2;:1-11. PubMed: 31793392

PAPER Potter H, Chial HJ, Caneus J, Elos M, Elder N, Borysov S, Granic A

Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders.

Front Genet. 2019;10:1092. Epub 2019 Nov 7 PubMed: 31788001

PAPER Prokopenko I, Miyakawa G, Zheng B, Heikkinen J, Petrova Quayle D, Udeh-Momoh C, Claringbould A, Neumann J, Haytural H, Kaakinen MA, Loizidou E, Meissner E, Bertram L, BIOS consortium, Gveric DO, Gentleman SM, Attems J, Perneczky R, Arzberger T, Muglia P, Lill CM, Parkkinen L, Middleton LT

Alzheimer's disease pathology explains association between dementia with Lewy bodies and APOE-ε4/TOMM40 long poly-T repeat allele variants.

Alzheimers Dement (N Y). 2019;5:814-824. Epub 2019 Nov 20 PubMed: 31788537

Jaewoo lim

KRIBB
Korea, Republic of

ALZ-801

THERAPEUTICS Alzheon Inc. valiltramiprosate NRM-8499 homotaurine prodrug 3-APS Small Molecule Amyloid-Related Alzheon published results of a Phase 1 study of safety, tolerability, and pharmacokinetics of single and multiple doses of ALZ-801 in 127 healthy, old volunte

Christopher Janson on Gene Therapies Enter Trials for Many Brain Pathologies—What about AD?

COMMENT A great deal of preclinical work in gene therapy for diverse neurological diseases has been conducted over the past 20 years. The technologies for both antisense and viral-vector-based delivery are finally becoming mature, and without a doubt will be appl

Kristen Whitney

Richard Daneman on Single-Cell Expression Atlas Charts Changes in Alzheimer’s Entorhinal Cortex

COMMENT Grubman et al. present a data set of single nuclei sequencing of entorhinal cortex tissue derived from the brains of six Alzheimer’s disease (AD) patients and six age-matched control patients. This report, combined with the data set recently published by

Jonathon Buckley

Dementia Services
Sheffield, United Kingdom