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High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.

Arch Neurol. 1998 Jul;55(7):937-45. PubMed: 9678311

PAPER Angelis P, Scharf S, Mander A, Vajda F, Christophidis N

Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease.

Neurosci Lett. 1998 Mar 13;244(2):106-8. PubMed: 9572596

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Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease.

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Anatomical and physiological plasticity of dendritic spines.

Annu Rev Neurosci. 2007;30:79-97. PubMed: 17280523

Stephen Schmidt

United States

Byoung Gwag

Ajou University School of Medicine
Suwon, Korea, Republic of

Aβ Oligomers and NMDA Receptors—One Target, Two Toxicities

RESEARCH NEWS 2007-03-15 Research News Two new publications add to growing evidence that toxic Aβ oligomers play havoc with neurons by interfering with N-methyl-D-aspartate (NMDA)-type glutamate receptors (NMDARs) and Ca2+ flow, but they suggest different toxic mechanisms. The fi

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The gestational environment and Parkinson's disease: evidence for neurodevelopmental origins of a neurodegenerative disorder.

Reprod Toxicol. 2007 Apr-May;23(3):457-70. PubMed: 17350799

PAPER Gopinath S, Blair IP, Kennerson ML, Durnall JC, Nicholson GA

A novel locus for distal motor neuron degeneration maps to chromosome 7q34-q36.

Hum Genet. 2007 Jun;121(5):559-64. PubMed: 17354000

PAPER Li L, Yun SH, Keblesh J, Trommer BL, Xiong H, Radulovic J, Tourtellotte WG

Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory.

Mol Cell Neurosci. 2007 May;35(1):76-88. PubMed: 17350282

PAPER Brightwell JJ, Smith CA, Neve RL, Colombo PJ

Long-term memory for place learning is facilitated by expression of cAMP response element-binding protein in the dorsal hippocampus.

Learn Mem. 2007 Mar;14(3):195-9. PubMed: 17351144

PAPER Deng H, Le WD, Hunter CB, Mejia N, Xie WJ, Jankovic J

A family with Parkinson disease, essential tremor, bell palsy, and parkin mutations.

Arch Neurol. 2007 Mar;64(3):421-4. PubMed: 17353387

PAPER Roberti MJ, Bertoncini CW, Klement R, Jares-Erijman EA, Jovin TM

Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged alpha-synuclein.

Nat Methods. 2007 Apr;4(4):345-51. PubMed: 17351621

PAPER Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH

Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report.

Arch Neurol. 2007 Mar;64(3):431-4. PubMed: 17353389

PAPER Van Raamsdonk JM, Warby SC, Hayden MR

Selective degeneration in YAC mouse models of Huntington disease.

Brain Res Bull. 2007 Apr 30;72(2-3):124-31. PubMed: 17352936