PAPER Li A, Xie Z, Dong Y, McKay KM, McKee ML, Tanzi RE

Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes.

Hum Mol Genet. 2007 Nov 1;16(21):2626-39. PubMed: 17704509

ATF-2 phos Ser490/498

ANTIBODY polyclonal manufacturer Cat# PS1001 immunogen = synthetic phosphopeptide corresp to amino acids surrounding the Ser490/498 phosphorylation site of human ATF2 liquid, saline, HEPES, BSA, glycerol, no preservative recognizes the ~50 kDa ATF2 protein, phosph

CREB

ANTIBODY polyclonal manufacturer Cat# CBA071 Immunogen = synthetic peptide corresp. to aa surrounding Ser133 of human CREB capture ab = mono CREB; detector ab = rabbit Anti-CREB total detects and quantifies the level of CREB (cAMP-Response Element-Binding protein)

CREB phos Ser133

ANTIBODY kit manufacturer Cat# CBA072 Immunogen = synthetic phospho-peptide (K R R E I L S R R P pS Y R K) corresp. to aa 123-136 of human CREB anti-CREB capture ab; rabbit anti-CREB (pSer133) detector ab detects and quantifies the level of CREB (cAMP-Response Ele

CREB2

ANTIBODY polyclonal manufacturer Cat# PC715 Immunogen = synthetic peptide (E E V R K A R G K K R V P) corresp. to aa 339-351 of human ATF4 liquid, TBS, BSA, azide recognizes the ~40 kDa ATF4 protein (CREB2) IgG CREB, cAMP, CBP Calbiochem EMD Biosciences Goat Human

CRE-BP1 phos Thr71

ANTIBODY polyclonal manufacturer Cat# ST1075 Immunogen = a synthetic phosphopeptide corresp. to aa surrounding the Thr71 phosphorylation site of human ATF-2 liquid, HEPES, NaCl, BSA, glycerol, affinity purified recognizes the ~70 kDa ATF-2 protein phosphorylated a

CRE-BP1 phos ser490/498

ANTIBODY polyclonal manufacturer Cat# PS1001 Immunogen = synthetic phosphopeptide corresp. to amino acids surrounding the Ser490/498 phosphorylation site of human ATF2 liquid, HEPES, NaCl, BSA, glycerol, affinity purified recognizes the ~50 kDa ATF2 protein, phosp

CaM Kinase II

ANTIBODY polyclonal manufacturer Cat# 208703 Immunogen = synthetic peptide corresp. to 14 aa (7-20, N-terminal), C T R F T D E Y Q L F E E L, based on the rat CaM Kinase II delta isoform, conj. to KLH liquid, Tris-glycine, azide, affinity purified CaM Kinase II al

ATF-2 phos Thr69/71

ANTIBODY polyclonal manufacturer Cat# 3359-100 liquid, PBS, glycerol, BSA, azide, affinity purified ATF-2 (CRE-BP1) phosphorylated Thr69/71 CREB, cAMP, CBP BioVision Rabbit Human Mouse Rat ATF-2 phos Thr69/71 http://alzforum.org/res/com/ant/default.asp?antibodyID=

ATF-2

ANTIBODY polyclonal manufacturer Cat# 3358-100 immunogen = synthetic peptide mapping to the N-terminus of human ATF-2 liquid, PBS, glycerol, BSA, thimerosal, affinity purified CRE-BP1 (ATF-2) CREB, cAMP, CBP BioVision Rabbit Human Mouse Rat ATF-2 http://alzforum.o

CaMKII phos Thr286

ANTIBODY polyclonal manufacturer Cat# 3384-100 liquid, PBS, glycerol, BSA, thimerosal, affinity purified CaMKII phosphorylated Thr286 CaM Kinase II (CAMKII) BioVision Rabbit Human Mouse Rat CaMKII phos Thr286 http://alzforum.org/res/com/ant/default.asp?antibodyID=

Fred Van Leuven on The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.

COMMENT I stand in awe of this painstaking, comprehensive study from Ulrike Müller and coworkers. This is probably as close as we can get to the function of APP and the amyloid peptides in vivo—and to the problem of their physiological function and pathological r

Vanessa Morais on Local Control: Dendritic BC1 RNA Regulates Dopamine Receptor Levels

COMMENT The Brain Cytoplasmic RNA BC1 Regulates Dopamine D2 Receptor Mediated Transmission in the Striatum The work performed by Centonze et al. (Centonze et al., 2007) identifies BC1 RNA as a regulator of dopamine (DA) transmission in the striatum. Interestingly

PAPER Centonze D, Rossi S, Napoli I, Mercaldo V, Lacoux C, Ferrari F, Ciotti MT, De Chiara V, Prosperetti C, Maccarrone M, Fezza F, Calabresi P, Bernardi G, Bagni C

The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum.

J Neurosci. 2007 Aug 15;27(33):8885-92. PubMed: 17699670

CaMKII

ANTIBODY polyclonal manufacturer Cat# 3383-100 liquid, PBS, glycerol, BSA, azide, affinity purified 50 kDa CaMKII CaM Kinase II (CAMKII) BioVision Rabbit Human Mouse Rat CaMKII http://alzforum.org/res/com/ant/default.asp?antibodyID=22502