Chromogranin A

ANTIBODY polyclonal manufacturer Cat# AB9254 immunogen = recombinant human chromogranin A liquid, PBS, azide, affinity purified chromogranin A Secreted Neuropeptides & Receptors Chemicon and Upstate are Millipore Rabbit Human Monkey Rat Chromogranin A http://a

Chromogranin A (PHE5)

ANTIBODY monoclonal PHE5 manufacturer Cat# MAB319 immunogen = Human pheochromocytoma liquid, purified Ig, PBS, azide Chromogranin A <em>not</em> rat, mouse; others not tested IgG₁ Secreted Neuropeptides & Receptors Chemicon a

Caitlin O'Brien

Stanford University
Philadelphia, United States

p35 (ES19, ES24)

ANTIBODY monoclonal ES19, ES24 manufacturer Cat# 05-380<br />Reference: <br /><a href="/papers/regulation-tau-pathology-microglial-fractalkine-receptor" target="_new">Bhaskar K, 2010</a> immunogen = recombinant human p35

Cdk5 (DC17)

ANTIBODY monoclonal DC17 manufacturer Cat# 05-364 immunogen = recombinant human cdk5 protein A, Tris-glycine, azide 33 kDa Cdk5 IgG_2a Cell Cycle Upstate and Chemicon are Millipore Mouse Human Mouse Rat Drosophila Cdk5 http://alzforum.org/res

Cdk4

ANTIBODY polyclonal manufacturer Cat# 07-659 immunogen = synthetic peptide corresp. to aa 291-303 tris-glycine saline, glycerol, azide, affinity purified cdk4 other species not tested IgG Cell Cycle Upstate and Chemicon are Millipore Rabbit Human Mouse Cdk4 http:/

Cdk4

ANTIBODY polyclonal manufacturer Cat# 06-139 immunogen = peptide corresp. in sequence to epitopes contained within the C-terminal domain of human cdk4 liquid, tris-glycine, NaCl, azide, protein G purified cdk4 other species not tested IgG Cell Cycle Upstate and Ch

Cdk4 (DCS-35)

ANTIBODY monoclonal DCS-35 manufacturer Cat# MAB8879 immunogen = purified recombinant cdk4 protein. liquid, PBS, BSA, azide, purified p34 or cyclin-dependent kinase 4 (cdk4); no cross-reaction with other cdks kinase assay IgG₁,κ Cell Cycle C

Elizabeth Heilig

Massachusetts General Hospital
Boston, United States

Tsuneya Ikezu on Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.

COMMENT We would like to thank Drs. Tobinick, Sastre, and colleagues for their constructive comments. In accord, all of these studies are pointing to the importance of anti-inflammatory therapy for preventing gliosis-mediated Aβ production. Since accelerated glio

Ming Chen on Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.

COMMENT The puzzle of how presenilin (PS) mutations cause familial AD (FAD) is of great importance because, as many believe, it may relate to the origin of sporadic AD. Based on my critical analysis of the research data in comparison with AD features, I deduced a

Mary Reid on The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.

COMMENT Cheryl Wellington and colleagues report that ABCG1 modulates the subcellular distribution and proteolytic processing of β amyloid precursor protein and that ABCG1 mRNA levels are twofold more abundant in Down syndrome brain compared to age- and sex-matche

PAPER Out R, Hoekstra M, Meurs I, de Vos P, Kuiper J, Van Eck M, Van Berkel TJ

Total body ABCG1 expression protects against early atherosclerotic lesion development in mice.

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):594-9. PubMed: 17204665

PAPER Marmillot P, Patel S, Lakshman MR

Reverse cholesterol transport is regulated by varying fatty acyl chain saturation and sphingomyelin content in reconstituted high-density lipoproteins.

Metabolism. 2007 Feb;56(2):251-9. PubMed: 17224341

PAPER Kobayashi A, Takanezawa Y, Hirata T, Shimizu Y, Misasa K, Kioka N, Arai H, Ueda K, Matsuo M

Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1.

J Lipid Res. 2006 Aug;47(8):1791-802. PubMed: 16702602