COX-3

ANTIBODY polyclonal manufacturer Cat# 07-587 immunogen = peptide corresp. to aa 1-12 (M S R E F D P E A P R N) of canine COX-3 liquid, tris-glycine saline, azide, glycerol COX-3 other species not tested IgG COX1, COX2, COX3, COX IV Upstate and Chemicon are Millipo

COX-2

ANTIBODY polyclonal manufacturer Cat# 07-693 immunogen = synthetic peptide (S H S R L D D I N P T V L I K) corresp. to aa 584-598 of rat cyclooxygenase-2 (COX-2) liquid, PBS, BSA, glycerol, azide, affinity purified COX-2; no cross reaction with COX-1 other species

COX-1

ANTIBODY monoclonal manufacturer Cat# MAB5586 immunogen = purified sheep Cox-1 liquid, purified Ig, Tris, azide COX-1 other species not tested IgG_2b COX1, COX2, COX3, COX IV Chemicon and Upstate are Millipore Mouse Bovine Sheep Human Mouse R

Mary McLarnon

Retired
Mamaroneck, United States

Those Elusive AICD Targets: Neprilysin Questioned

RESEARCH NEWS 2007-02-21 Research News The current issue of Neuron contains a scientific debate that bears watching. It is about one of the great mysteries of amyloid-β precursor protein (APP), that is, its physiological role. Scientists know a fair amount about APP cleavage and

Debashis Mukhopadhyay

Saha Institute of Nuclear Physics
Kolkata, India

PAPER Kuhn J, Bewermeyer H, Miyajima H, Takahashi Y, Kuhn KF, Hoogenraad TU

Treatment of symptomatic heterozygous aceruloplasminemia with oral zinc sulphate.

Brain Dev. 2007 Aug;29(7):450-3. PubMed: 17307325

PAPER Semmler A, Frisch C, Debeir T, Ramanathan M, Okulla T, Klockgether T, Heneka MT

Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model.

Exp Neurol. 2007 Apr;204(2):733-40. PubMed: 17306796

PAPER Jia Z, Misra HP

Exposure to mixtures of endosulfan and zineb induces apoptotic and necrotic cell death in SH-SY5Y neuroblastoma cells, in vitro.

J Appl Toxicol. 2007 Sep-Oct;27(5):434-46. PubMed: 17309119

PAPER Ryu H, Ferrante RJ

Translational therapeutic strategies in amyotrophic lateral sclerosis.

Mini Rev Med Chem. 2007 Feb;7(2):141-50. PubMed: 17305588

PAPER Aisa B, Tordera R, Lasheras B, Del Río J, Ramírez MJ

Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats.

Psychoneuroendocrinology. 2007 Apr;32(3):256-66. PubMed: 17307298

PAPER Chung CH, Kurien BT, Mehta P, Mhatre M, Mou S, Pye QN, Stewart C, West M, Williamson KS, Post J, Liu L, Wang R, Hensley K

Identification of lanthionine synthase C-like protein-1 as a prominent glutathione binding protein expressed in the mammalian central nervous system.

Biochemistry. 2007 Mar 20;46(11):3262-9. PubMed: 17305318

PAPER Sarkar S, Davies JE, Huang Z, Tunnacliffe A, Rubinsztein DC

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

J Biol Chem. 2007 Feb 23;282(8):5641-52. PubMed: 17182613

PAPER Fujita M, Sugama S, Nakai M, Takenouchi T, Wei J, Urano T, Inoue S, Hashimoto M

alpha-Synuclein stimulates differentiation of osteosarcoma cells: relevance to down-regulation of proteasome activity.

J Biol Chem. 2007 Feb 23;282(8):5736-48. PubMed: 17189270

PAPER Johnson GL, Nakamura K

The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.

Biochim Biophys Acta. 2007 Aug;1773(8):1341-8. PubMed: 17306896