Tommaso Russo on Aβ's Shadowy Sibling—What Becomes of the Intracellular Domain?

COMMENT The observation that AICD and Fe65 are nuclear proteins (Minopoli et al., 2001; Kimberly et al., 2001; Cao & Sudhof, 2001; Gao & Pimplikar, 2001) and the similar proteolytic processing of APP and Notch have suggested the hypothesis that APP and ...

Sheila McGuire

United States

Edward Koo on Aβ's Shadowy Sibling—What Becomes of the Intracellular Domain?

COMMENT In this paper, Scheinfeld and colleagues from the D’Adamio laboratory extended their work on the interaction between JIP-1 and APP. JIP is JNK-interacting protein-1, which several groups, including the D’Adamio lab, last year showed to bind to the ...

Scott Small on Mutant AβPP Retards Growth in Hippocampus before Plaques Form

COMMENT When introduced as a clinical tool in the 1980s, MRI transformed the field of clinical neuroscience. Visualizing the brain with exquisite anatomical resolution was one thing, but to accomplish this feat noninvasively, so that human subjects could be ...

'Afa Palu

Provo, United States

Susanne Nyström

Sweden

rebecca thompson

Research Institute for the Care of the Elderly

Claudio Machiaverni

Sao Paulo, Brazil

Christine Nicole Dacanay

Philippines

PAPER Kurisaki H, Yomono H, Murayama S, Hebisawa A

[Multiple system atrophy with a-/hypo-ceruloplasminemia: distribution of iron in brains of 2 autopsy cases].

Rinsho Shinkeigaku. 2002 Apr;42(4):293-8. PubMed: 12561083

PAPER Perry VH, Newman TA, Cunningham C

The impact of systemic infection on the progression of neurodegenerative disease.

Nat Rev Neurosci. 2003 Feb;4(2):103-12. PubMed: 12563281

PAPER Pereira E

Diffusion-weighted sequence on MRI for the diagnosis of Creutzfeldt-Jakob disease.

Arq Neuropsiquiatr. 2002 Dec;60(4):906-8. PubMed: 12563377

PAPER Chung SY, Han SH

Melatonin attenuates kainic acid-induced hippocampal neurodegeneration and oxidative stress through microglial inhibition.

J Pineal Res. 2003 Mar;34(2):95-102. PubMed: 12562500

PAPER Rideout HJ, Dietrich P, Savalle M, Dauer WT, Stefanis L

Regulation of alpha-synuclein by bFGF in cultured ventral midbrain dopaminergic neurons.

J Neurochem. 2003 Feb;84(4):803-13. PubMed: 12562524

PAPER Dinkel K, MacPherson A, Sapolsky RM

Novel glucocorticoid effects on acute inflammation in the CNS.

J Neurochem. 2003 Feb;84(4):705-16. PubMed: 12562515