PAPER Bonkowski MS, Rocha JS, Masternak MM, Al Regaiey KA, Bartke A

Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7901-5. PubMed: 16682650

PAPER Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.

Nat Genet. 2008 Apr;40(4):392-4. PubMed: 18311139

PAPER Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA

Mitochondrial point mutations do not limit the natural lifespan of mice.

Nat Genet. 2007 Apr;39(4):540-3. PubMed: 17334366

hnRNP C1/C2 (4F4)

ANTIBODY monoclonal 4F4 laboratory (<a href="http://www.hhmi.org/research/investigators/dreyfuss.html" target="_new">G Dreyfuss</a><br />Howard Hugues Medical Institute)<br /><a href="http://www.jcb.org/cgi/repri

hnRNP A1 (4B10)

ANTIBODY monoclonal 4B10 laboratory (<a href="http://www.hhmi.org/research/investigators/dreyfuss.html" target="_new">G Dreyfuss</a><br />Howard Hugues Medical Institute)<br /><a href="http://www.genesdev.org/cgi

How Sweet It Is! Longevity Linked to Insulin-like Growth Factor Signaling

RESEARCH NEWS 2008-03-06 Research News Only one in 10,000 people gets to be serenaded with the “Happy Birthday” song for the 100th time. For some of them, reaching that magic number may have more to do with genetics than clean living. In this week’s PNAS, researchers led by Nir B

Power Outage—Damaged Mitochondria In PET Changes, Early Aging

RESEARCH NEWS 2008-03-06 Research News Mitochondria get more than their fair share of the blame for neurodegeneration, being linked to Alzheimer, Parkinson, Huntington diseases, and even normal aging. Recent papers offer little respite for these energy-generating organelles. In t

PAPER Madsen EC, Morcos PA, Mendelsohn BA, Gitlin JD

In vivo correction of a Menkes disease model using antisense oligonucleotides.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3909-14. PubMed: 18316734

PAPER Wu DM, Lu J, Zheng YL, Zhou Z, Shan Q, Ma DF

Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins.

Neurobiol Learn Mem. 2008 Jul;90(1):19-27. PubMed: 18316211

PAPER Yamazaki M, Someya Y, Aramomi M, Masaki Y, Okawa A, Koda M

Infection-related atlantoaxial subluxation (Grisel syndrome) in an adult with Down syndrome.

Spine (Phila Pa 1976). 2008 Mar 1;33(5):E156-60. PubMed: 18317184

PAPER Entezam A, Usdin K

ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.

Nucleic Acids Res. 2008 Feb;36(3):1050-6. PubMed: 18160412

PAPER Wadsworth JD, Joiner S, Linehan JM, Desbruslais M, Fox K, Cooper S, Cronier S, Asante EA, Mead S, Brandner S, Hill AF, Collinge J

Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3885-90. PubMed: 18316717

PAPER Lee JK, Shin JH, Suh J, Choi IS, Ryu KS, Gwag BJ

Tissue inhibitor of metalloproteinases-3 (TIMP-3) expression is increased during serum deprivation-induced neuronal apoptosis in vitro and in the G93A mouse model of amyotrophic lateral sclerosis: a potential modulator of Fas-mediated apoptosis.

Neurobiol Dis. 2008 May;30(2):174-85. PubMed: 18316197

PAPER Kabashi E, Agar JN, Hong Y, Taylor DM, Minotti S, Figlewicz DA, Durham HD

Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis.

J Neurochem. 2008 Jun 1;105(6):2353-66. PubMed: 18315558

PAPER Chiba T, Fujita S, Kubota H, Inoue D, Mizuno A, Komatsu T, Yamaza H, Higami Y, Shimokawa I

Identification of fasting-induced genes in the rat hypothalamus: relationship with neuroprotection.

Ann N Y Acad Sci. 2007 Nov;1119:216-26. PubMed: 18056970