Katherine Youmans on Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis.
COMMENT The new reports by Kim et al. are very intriguing, as they provide evidence that contradicts over a decade of research indicating that ApoE is required for Aβ deposition. Given the novelty of these results, a primary concern is that the authors establish ...