Konstanze Winklhofer on Form or Function: How Does Pink1 Deficiency Mar Mitochondria?

COMMENT Accumulating evidence indicates that mitochondrial dysfunction is a key factor in the pathophysiology of Parkinson disease (PD). Inhibitors of complex I of the electron transport chain, such as MPTP and rotenone, can induce parkinsonism, and a decreased ...

Konstanze Winklhofer on Parkin deficiency increases vulnerability to inflammation-related nigral degeneration.

COMMENT The etiopathogenesis of sporadic Parkinson disease (PD) is only poorly understood. Over the past decade, several genes have been linked to monogenic familial variants of PD, which can provide insight into the pathomechanisms and allow the generation of PD ...

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Konstanze Winklhofer on Form or Function: How Does Pink1 Deficiency Mar Mitochondria?

Konstanze Winklhofer on Parkin deficiency increases vulnerability to inflammation-related nigral degeneration.

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