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Robert Vassar on Peer Pressure? "Pal" Leads APP Down Amyloid Path

COMMENT The paper by Kovacs and colleagues reports the discovery that a significant proportion of APP in the cell is palmitoylated and enriched in lipid rafts. APP palmitoylation increased the colocalization of APP with BACE1, the β-secretase. Consequently, BACE1 ...

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