4 RESULTS
COMMENT These data add to the currently emerging evidence for an AD signature being detectable in blood. It is interesting that Aβ42 is identified by the random forest model, which is in line with other recent evidence of Aβ reductions in blood and CSF. It is not ...
COMMENT The interesting aspect of this study is that the longitudinal decrease in biomarkers observed in the familial DIAN cohort is now replicated in the ADNI cohort of LOAD patients. Such longitudinal data are highly needed for clinical trials, and the observed ...
COMMENT Qin et al. have undertaken a meta-analysis of peripheral blood cytokine levels in Parkinson’s disease compared to healthy controls, using data on 1,547 PD patients and 1,107 controls from 25 studies. They showed that peripheral levels of IL-6, TNF-α, Il1β ...
COMMENT This paper by Irwin at al. raises some important points. For a study on CSF frontotemporal dementia (FTD) biomarkers, they managed to collect a relatively fair number of patients. Also, the postmortem confirmation is a strong point, as FTD is ...
